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婴儿智力发育中的迟缓与双胞胎一致性:重新评估

Retardation and twin concordance in infant mental development: a reassessment.

作者信息

Wilson R S, Matheny A P

出版信息

Behav Genet. 1976 Jul;6(3):353-8. doi: 10.1007/BF01065730.

DOI:10.1007/BF01065730
PMID:987783
Abstract

A reappraisal is made of Nichols and Broman's conclusion that there is no evidence that genetic influences are important in infant mental development if severely retarded twins are excluded from the sample. The reappraisal touches on certain idiosyncrasies of their sample, the test scores reported, and their definition of severe retardation. Data are presented for a sample of White twins who have been followed longitudinally since birth. For Bayley Mental Scale scores at 9 months of age, the monozygotic within-pair correlation was 0.85 and the dizygotic within-pair correlation was 0.62. With 13 retarded twins excluded, the correlations became 0.81 and 0.64, respectively, with the monozygotic correlation still being significantly larger (p less than 0.01). The present results indicate that genetic factors play a role in infant mental development.

摘要

对尼科尔斯和布罗曼的结论进行了重新评估,他们的结论是,如果从样本中排除重度智障双胞胎,就没有证据表明基因影响在婴儿智力发育中起重要作用。重新评估涉及他们样本的某些特质、所报告的测试分数以及他们对重度智障的定义。给出了自出生以来一直进行纵向跟踪的白人双胞胎样本的数据。对于9个月大时的贝利智力量表分数,同卵双胞胎对内相关性为0.85,异卵双胞胎对内相关性为0.62。排除13对智障双胞胎后,相关性分别变为0.81和0.64,同卵双胞胎的相关性仍然显著更大(p小于0.01)。目前的结果表明,遗传因素在婴儿智力发育中起作用。

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本文引用的文献

1
COMPARISONS OF MENTAL AND MOTOR TEST SCORES FOR AGES 1-15 MONTHS BY SEX, BIRTH ORDER, RACE, GEOGRAPHICAL LOCATION, AND EDUCATION OF PARENTS.按性别、出生顺序、种族、地理位置及父母教育程度对1至15个月婴儿的心理和运动测试分数进行比较。
Child Dev. 1965 Jun;36:379-411.
2
Familial mental retardation: a continuing dilemma.家族性智力迟钝:一个持续存在的难题。
Science. 1967 Jan 20;155(3760):292-8. doi: 10.1126/science.155.3760.292.