Dividing the empire: boundary chromatin elements delimit the territory of enhancers.
作者信息
Udvardy A
机构信息
Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, H-6701 Szeged, PO Box 521, Hungary.
出版信息
EMBO J. 1999 Jan 4;18(1):1-8. doi: 10.1093/emboj/18.1.1.
Abstract
摘要
相似文献
1
Dividing the empire: boundary chromatin elements delimit the territory of enhancers.分割帝国：边界染色质元件界定增强子区域
EMBO J. 1999 Jan 4;18(1):1-8. doi: 10.1093/emboj/18.1.1.
2
The insulation of genes from external enhancers and silencing chromatin.基因与外部增强子及沉默染色质的隔离。
Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4(Suppl 4):16433-7. doi: 10.1073/pnas.162342499. Epub 2002 Aug 1.
3
Communication over a large distance: enhancers and insulators.远距离通讯：增强子与绝缘子
Biochem Cell Biol. 2003 Jun;81(3):241-51. doi: 10.1139/o03-051.
4
TRAPping enhancer function.捕获增强子功能。
Nat Genet. 2002 Dec;32(4):555-6. doi: 10.1038/ng1202-555.
5
Chromatin looping and the probability of transcription.染色质环化与转录概率
Trends Genet. 2006 Apr;22(4):197-202. doi: 10.1016/j.tig.2006.02.004. Epub 2006 Feb 21.
6
Long-range chromatin regulatory interactions in vivo.体内远距离染色质调控相互作用。
Nat Genet. 2002 Dec;32(4):623-6. doi: 10.1038/ng1051. Epub 2002 Nov 11.
7
Organizing the genome: enhancers and insulators.基因组的组织：增强子与绝缘子
Biochem Cell Biol. 2005 Aug;83(4):516-24. doi: 10.1139/o05-054.
8
[Mechanisms of distant enhancer action on DNA and in chromatin].[远距离增强子对DNA及染色质作用的机制]
Mol Biol (Mosk). 2009 Mar-Apr;43(2):204-14.
9
Boundary swapping in the Drosophila Bithorax complex.果蝇双胸复合体中的边界交换
Development. 2008 Dec;135(24):3983-7. doi: 10.1242/dev.025700. Epub 2008 Nov 5.
10
Unraveling cis-regulatory mechanisms at the abdominal-A and Abdominal-B genes in the Drosophila bithorax complex.解析果蝇双胸复合体中腹A基因和腹B基因的顺式调控机制。
Dev Biol. 2006 May 15;293(2):294-304. doi: 10.1016/j.ydbio.2006.02.015. Epub 2006 Mar 20.
引用本文的文献
1
Transposable element-derived sequences in vertebrate development.脊椎动物发育过程中可转座元件衍生的序列。
Mob DNA. 2021 Jan 6;12(1):1. doi: 10.1186/s13100-020-00229-5.
2
Mechanism of chromosomal boundary action: roadblock, sink, or loop?染色体边界作用的机制：路障、汇流还是环？
Genetics. 2011 Mar;187(3):731-48. doi: 10.1534/genetics.110.123752. Epub 2010 Dec 31.
3
Drosophila mini-white model system: new insights into positive position effects and the role of transcriptional terminators and gypsy insulator in transgene shielding.果蝇 mini-white 模型系统：正向位置效应及转录终止子和 gypsy 绝缘子在转基因屏蔽中作用的新见解。
Nucleic Acids Res. 2010 Jan;38(1):39-47. doi: 10.1093/nar/gkp877. Epub 2009 Oct 23.
4
Pairing between gypsy insulators facilitates the enhancer action in trans throughout the Drosophila genome.吉普赛绝缘子之间的配对促进了增强子在整个果蝇基因组中的反式作用。
Mol Cell Biol. 2005 Nov;25(21):9283-91. doi: 10.1128/MCB.25.21.9283-9291.2005.
5
Formation of a large, complex domain of histone hyperacetylation at human 14q32.1 requires the serpin locus control region.
Nucleic Acids Res. 2005 Jun 7;33(10):3313-22. doi: 10.1093/nar/gki645. Print 2005.
6
The Mcp element from the bithorax complex contains an insulator that is capable of pairwise interactions and can facilitate enhancer-promoter communication.来自双胸复合体的Mcp元件包含一个绝缘子，该绝缘子能够进行成对相互作用并促进增强子与启动子之间的通讯。
Mol Cell Biol. 2005 May;25(9):3682-9. doi: 10.1128/MCB.25.9.3682-3689.2005.
7
Regulated chromatin domain comprising cluster of co-expressed genes in Drosophila melanogaster.果蝇中包含共表达基因簇的调控染色质结构域。
Nucleic Acids Res. 2005 Mar 8;33(5):1435-44. doi: 10.1093/nar/gki281. Print 2005.
8
The enhancer-blocking activity of the Fab-7 boundary from the Drosophila bithorax complex requires GAGA-factor-binding sites.果蝇双胸复合体中Fab-7边界的增强子阻断活性需要GAGA因子结合位点。
Genetics. 2004 Nov;168(3):1371-84. doi: 10.1534/genetics.104.029561.
9
Drosophila Su(Hw) insulator can stimulate transcription of a weakened yellow promoter over a distance.果蝇的Su(Hw)绝缘子能够在一定距离上刺激弱化的黄色启动子的转录。
Genetics. 2005 Jul;170(3):1133-42. doi: 10.1534/genetics.104.034587. Epub 2004 Nov 1.
10
Heritable transgene expression pattern imposed onto maize ubiquitin promoter by maize adh-1 matrix attachment regions: tissue and developmental specificity in maize transgenic plants.玉米adh-1基质附着区域赋予玉米泛素启动子的可遗传转基因表达模式：玉米转基因植株中的组织和发育特异性
Plant Cell Rep. 2004 Jul;22(12):931-8. doi: 10.1007/s00299-004-0779-x. Epub 2004 May 4.
本文引用的文献
1
Chromatin interaction mechanism of transcriptional control in vivo.体内转录调控的染色质相互作用机制。
EMBO J. 1998 Oct 15;17(20):6020-7. doi: 10.1093/emboj/17.20.6020.
2
Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators.转基因转录活性的丧失伴随着DNA甲基化和组蛋白去乙酰化，并且可被绝缘子阻止。
Genes Dev. 1998 Sep 15;12(18):2852-62. doi: 10.1101/gad.12.18.2852.
3
The scs and scs' insulator elements impart a cis requirement on enhancer-promoter interactions.scs和scs的绝缘子元件对增强子-启动子相互作用施加了顺式需求。
Mol Cell. 1998 Jan;1(2):301-8. doi: 10.1016/s1097-2765(00)80030-1.
4
The effect of distance on long-range chromatin interactions.距离对长程染色质相互作用的影响。
Mol Cell. 1997 Dec;1(1):131-9. doi: 10.1016/s1097-2765(00)80014-3.
5
Polycomb and trithorax group proteins mediate the function of a chromatin insulator.多梳蛋白和三胸节蛋白家族介导染色质绝缘子的功能。
Cell. 1998 Feb 20;92(4):511-21. doi: 10.1016/s0092-8674(00)80944-7.
6
Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights.哺乳动物β-珠蛋白基因簇的位点控制区：结合系统发育分析与实验结果以获得功能见解
Gene. 1997 Dec 31;205(1-2):73-94. doi: 10.1016/s0378-1119(97)00474-5.
7
The chicken lysozyme locus as a paradigm for the complex developmental regulation of eukaryotic gene loci.
J Biol Chem. 1997 Oct 17;272(42):26075-8. doi: 10.1074/jbc.272.42.26075.
8
Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues.相邻的DNA元件主要将一个新的染色质开放区域的普遍活性限制在特定组织中。
EMBO J. 1997 Aug 15;16(16):5037-45. doi: 10.1093/emboj/16.16.5037.
9
A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1.T细胞受体α/δ基因座处的靶向突变会损害T细胞发育，并揭示附近抗凋亡基因Dad1的存在。
Mol Cell Biol. 1997 Apr;17(4):2151-7. doi: 10.1128/MCB.17.4.2151.
10
The role of insulator elements in defining domains of gene expression.绝缘子元件在界定基因表达结构域中的作用。
Curr Opin Genet Dev. 1997 Apr;7(2):242-8. doi: 10.1016/s0959-437x(97)80134-7.
Zotero 插件