Evsikov A V, Solomko A P
Tsitol Genet. 1998 Apr-May;32(3):84-7.
It is found out that the acceleration of preimplantation morphogenesis is observed in mouse chimeras between single two-cell-stage blastomeres of BALB/c and [BALB/c x C57B1/6] x C57B1/6 (F2) embryos. The paired aggregation of blastomeres of two-cell stage made F2-BALB/c chimeras to start cavitation 8 +/- 2 hours earlier than F2<-->F2 and BALB/c-BALB/c control embryos. We have demonstrated for the first time the 'chimeric' heterosis on preimplantation stages. Possible approaches to the future studies of this phenomenon are discussed.
研究发现,在BALB/c单个体细胞期卵裂球与[BALB/c×C57B1/6]×C57B1/6(F2)胚胎构建的小鼠嵌合体中,观察到着床前形态发生加速现象。两细胞期卵裂球的配对聚集使F2-BALB/c嵌合体比F2<-->F2和BALB/c-BALB/c对照胚胎提前8±2小时开始出现空泡化。我们首次证明了着床前阶段的“嵌合”杂种优势。讨论了未来研究这一现象的可能方法。