Yoshida K, Hasegawa Y, Konishi N, Iwata H
Department of Orthopaedic Surgery, Aichi-ken Saiseikai Hospital, Nagoya, Japan.
Nagoya J Med Sci. 1998 Oct;61(3-4):131-5.
We employed hypotensive anesthesia with prostaglandin E1 (PGE1) and transfused 400 ml of autologous whole blood on the first postoperative day to avoid homologous blood transfusion in 137 patients undergoing rotational acetabular osteotomy (RAO) and RAO combined with intertrochanteric valgus osteotomy. Four hundred ml of whole blood were donated 1 week before the surgery, and transfused on the first postoperative day after hematological examination. We employed induced hypotension with PGE1 under general anesthesia with enflurane or isoflurane. Intraoperative systolic blood pressure was maintained at approximately 70-80 mmHg. The mean operation time was 139 +/- 32 minutes. The mean intraoperative and the postoperative estimated blood loss was 286 +/- 152 g and 259 +/- 122 g, respectively. The mean hemoglobin content was 13.3 +/- 1.1 g/dl before the operation. It showed the lowest value of 9.4 +/- 1.0 g/dl on the first postoperative day but it returned to 10.4 +/- 1.0 g/dl in the second postoperative week. There was no use of homologous blood transfusion. We consider that the concomitant use of autologous blood donation and hypotensive anesthesia is an extremely useful method to avoid homologous blood transfusion.
我们对137例行髋臼旋转截骨术(RAO)及RAO联合转子间外翻截骨术的患者采用前列腺素E1(PGE1)进行控制性低血压麻醉,并在术后第一天输注400ml自体全血,以避免异体输血。术前1周采集400ml全血,血液学检查后于术后第一天输注。我们在恩氟烷或异氟烷全身麻醉下用PGE1诱导控制性低血压。术中收缩压维持在约70 - 80mmHg。平均手术时间为139±32分钟。术中及术后估计平均失血量分别为286±152g和259±122g。术前平均血红蛋白含量为13.3±1.1g/dl。术后第一天血红蛋白含量降至最低值9.4±1.0g/dl,但在术后第二周回升至10.4±1.0g/dl。未使用异体输血。我们认为自体献血与控制性低血压麻醉联合使用是避免异体输血的一种非常有用的方法。