Matsuda M, Sakamoto H, Okamura T, Nakai Y, Ohashi Y, Kawabe J, Ochi H, Wakasa K
Department of Otorhinolaryngology, Osaka City University Medical School, Japan.
Acta Otolaryngol Suppl. 1998;538:214-20.
We studied the possible correlation between 2-18F-2-deoxy-D-glucose (FDG) uptake and histopathological findings in mass lesions of the parotid gland. Thirteen pleomorphic adenomas of the parotid gland were evaluated by computed tomography (CT), magnetic resonance imaging (MRI), Gallium scintigraphy, Technetium scintigraphy and FDG-positron emission tomography (PET). Standardized uptake values (SUV) and time-activity curves (TAC) were determined for all mass lesions. Pleomorphic adenomas were histologically classified into the following three types: epithelial, intermediate and mesenchymal, based on their dominant histological components. The numbers of epithelial, intermediate, and mesenchymal types were 5, 2, and 6, respectively. The levels of SUVs were 4.02 +/- 1.91 (range: 1.97-7.07) in the epithelial type, 5.05 +/- 1.12 (range: 4.26-5.58) in the intermediate type and 3.98 +/- 7.74 (range: 1.98-7.74) in the mesenchymal type, respectively. The accumulation of FDG did not differ significantly among the three types. Since the accumulation of FDG was significantly correlated with the tumor size, FDG-PET could reflect tumor growth ability more apparently than the other nuclear or imaging modalities.
我们研究了腮腺肿块病变中2-18F-2-脱氧-D-葡萄糖（FDG）摄取与组织病理学结果之间的可能相关性。通过计算机断层扫描（CT）、磁共振成像（MRI）、镓闪烁显像、锝闪烁显像和FDG正电子发射断层扫描（PET）对13例腮腺多形性腺瘤进行了评估。测定了所有肿块病变的标准化摄取值（SUV）和时间-活性曲线（TAC）。根据主要组织学成分，多形性腺瘤在组织学上分为以下三种类型：上皮型、中间型和间质型。上皮型、中间型和间质型的数量分别为5例、2例和6例。上皮型的SUV水平为4.02±1.91（范围：1.97-7.07），中间型为5.05±1.12（范围：4.26-5.58），间质型为3.98±7.74（范围：1.98-7.74）。三种类型之间FDG的积聚无显著差异。由于FDG的积聚与肿瘤大小显著相关，因此FDG-PET比其他核医学或影像学检查方法更能明显反映肿瘤的生长能力。
