MMWR Morb Mortal Wkly Rep. 1998 Dec 18;47(49):1070-3.
In 1996 and 1997, 153 cases of primary and secondary (P&S) syphilis were reported each year in Guilford County, North Carolina, a 147% increase from the 62 cases reported in 1994 (Figure 1). The incidence of P&S syphilis in Guilford County during 1996-1997 was 40.5 cases per 100,000 persons, substantially higher than the national health objective for 2000 of four cases per 100,000 (objective 19.3). In comparison, the number of P&S syphilis cases in North Carolina declined 57% from 1994 to 1997 (Figure 1), to a rate of 10.9 per 100,000 in 1997. This report summarizes the results of an investigation conducted by the Guilford County Health Department (GCHD), the North Carolina Division of Epidemiology, and CDC, which suggest this ongoing outbreak has been associated with missed opportunities for syphilis screening and treatment in high-risk settings, increased exchange of sex for money or drugs, and substantial rates of coinfection with syphilis and human immunodeficiency virus (HIV) among those tested.
1996年和1997年，北卡罗来纳州吉尔福德县每年报告153例一期和二期梅毒病例，比1994年报告的62例增加了147%（图1）。1996 - 1997年吉尔福德县一期和二期梅毒的发病率为每10万人40.5例，大大高于2000年每10万人4例的国家卫生目标（目标19.3）。相比之下，北卡罗来纳州一期和二期梅毒病例数从1994年到1997年下降了57%（图1），1997年降至每10万人10.9例。本报告总结了吉尔福德县卫生部门（GCHD）、北卡罗来纳州流行病学司和疾病控制与预防中心（CDC）开展的一项调查结果，这些结果表明，此次持续的疫情与高危环境中梅毒筛查和治疗机会的错失、以性换钱或毒品的交易增加以及接受检测者中梅毒与人类免疫缺陷病毒（HIV）的高合并感染率有关。
