Mascard E, Anract P, Touchene A, Pouillart P, Tomeno B
Service de chirurgie orthopédique, Hôpital Cochin, Paris.
Rev Chir Orthop Reparatrice Appar Mot. 1998 Nov;84(7):628-37.
The purpose of this study was to present the complications which occurred in knee replacement with the GUEPAR prosthesis, after bone tumor resection. We tried to point out complications in relation to prosthetic design and surgical technique.
Between 1972 and 1993, 90 patients had a knee resection, for 80 malignant and 10 benign tumors. There were 51 males and 49 females, aged 12 to 75 years (mean age 35). Fifty-six distal femur resections and 34 proximal tibial resections were performed. Length of resection averaged 16 cm (9 to 30). The reconstruction was always achieved with a cemented, custom-made GUEPAR prosthesis. Including revisions, there was a total of 102 prostheses in 90 patients. A patellar resurfacing was performed in 64 cases. An allograft reconstruction was associated in 39 knees. In all tibial resections and in two extra-articular femoral resections, the extensor mechanism had to be reconstructed. Several reconstruction techniques were associated, in which 19 medial gastrocnemius transfers. The prosthesis design was slightly modified with time. Ten patients received radiotherapy, and 55 had chemotherapy.
Results and complications were retrospectively assessed, with an average follow-up of 4.3 years (1 to 22). Six patients were lost for follow-up, 62 patients were alive, with no evolutive disease, 13 had an evolutive disease and 10 were deceased from disease. Nineteen patients had distant metastasis and 17 had local recurrences. Apart from intraoperative complications, late mechanical complications included: 13 aseptic loosening, 2 femoral shaft fractures, 18 knee contractures, 5 femoral stem fractures and, 18 intra-articular instabilities related to wear of the hinge-axis. In the 39 allograft-composite prostheses, only 15 had a favorable evolution. There were 15 extensor mechanism failures and 13 knees had persistent infection. There was a total of 94 reoperations in the 90 patients. In 28 cases, the initially implanted prosthesis was removed. There were also 18 revisions, 7 amputations and 3 arthrodeses. Survivorship analysis showed a 60 per cent probability for the initial prosthesis not to be revised at 10 year-follow-up, apart from oncologic complications.
Results with allograft-composite reconstruction were not better than with massive prosthesis. When needed, soft tissue coverage and patellar tendon augmentation would better be performed with gastrocnemius plasty. Polyethylene and steel bushes were not solution for hinge axis wear.
本研究的目的是介绍骨肿瘤切除术后使用GUEPAR假体进行膝关节置换时出现的并发症。我们试图指出与假体设计和手术技术相关的并发症。
1972年至1993年间,90例患者因80例恶性肿瘤和10例良性肿瘤接受了膝关节切除术。其中男性51例,女性49例,年龄12至75岁(平均年龄35岁)。进行了56例股骨远端切除术和34例胫骨近端切除术。切除长度平均为16厘米(9至30厘米)。重建均采用骨水泥固定的定制GUEPAR假体。包括翻修手术在内,90例患者共植入了102个假体。64例进行了髌骨表面置换。39例膝关节采用了同种异体骨重建。在所有胫骨切除术和2例关节外股骨切除术中,均需重建伸膝装置。采用了多种重建技术,其中19例进行了内侧腓肠肌转移。假体设计随时间略有修改。10例患者接受了放疗,55例接受了化疗。
对结果和并发症进行了回顾性评估,平均随访4.3年(1至22年)。6例患者失访,62例患者存活且无病情进展,13例有病情进展,10例死于疾病。19例患者发生远处转移,17例出现局部复发。除术中并发症外,晚期机械并发症包括:13例无菌性松动、2例股骨干骨折, 18例膝关节挛缩、5例股骨干骨折以及18例与铰链轴磨损相关的关节内不稳定。在39例同种异体骨复合假体中,只有l5例情况良好。发生了15例伸膝装置故障,13例膝关节持续感染。90例患者共进行了94次再次手术。28例患者取出了最初植入的假体。还进行了18次翻修、7次截肢和3次关节融合术。生存分析显示,除肿瘤并发症外,初次植入的假体在10年随访时不进行翻修的概率为60%。
同种异体骨复合重建的结果并不优于大块假体。必要时,采用腓肠肌成形术能更好地进行软组织覆盖和髌腱增强。聚乙烯和钢衬套无法解决铰链轴磨损问题。