Shinmura F, Yamamoto I, Koba T, Miwa T
No Shinkei Geka. 1976 Sep;4(9):883-8.
As a causative factor in spontaneous subarachnoid hemorrhage, vascular anomalies, especially aneurysm or arteriovenous malformation, have been generally recognized. On the other hand, subarachnoid hemorrhage from brain tumor and cryptic vascular malformation are rare. We experienced two cases showing subarachnoid hemorrhage from angioblastic meningioma and vascular hamartoma as an initial symptom. Case 1: A 48-year-old woman, who complained of severe headache and vomiting on Feb. 10th, 1972, gradually became lethargic. Lumbar puncture revealed moderately hemorrhagic C.S.F.. On the fifth day after the onset, she was admitted to our hospital. On admission she showed disorientation and disturbance of resent memory. Aphasia and agnosia were slightly observed. On ophthalmologic examination right homonymous lower quadrant hemianopsia was observed. The carotid angiogram showed slight square shift of the anterior cerebral artery to the right side, elevation of the middle serebral artery and a homogeneous tumor stain in the occipital region in capillary phase. A walnut sized tumor invading the middle portion of the left lateral sinus and showing firm adhesion to the tentrium was found. There was an intracerebral hematoma behined the tumor. The tumor, the tentrium and the lateral sinus were extirpated en bloc and the intracerebral hematoma was aspirated. Histologically, the tumor was angioblastic meningioma. Case 2: A 7-year-old boy, who complained of severe abrupt headache, nuchal pain and vomiting on Sept. 17th, 1972, became gradually lethargic. Lumbar puncture revealed hemorrhagic C.S.F., On the tenth day after the onset, he was admitted to our hospital. He showed confusion and agitation. The carotid angiogram showed an unrolling of the pericallosal artery, but no findings of space taking lesions. An air study indicated a globular filling defect protruding into the anterior horn of the right lateral ventricle. The tumor located in the laterobasal wall of the anterior horn was removed picemiel by transventricular approach. Histologically, the tumor was vascular hamartoma. Furthermore, we discussed various brain tumors showing subarachnoid hemorrhage as an initial symptom, its frequency and bleeding mechanism on the literature.
作为自发性蛛网膜下腔出血的一个致病因素,血管异常,尤其是动脉瘤或动静脉畸形,已得到普遍认可。另一方面,脑肿瘤和隐匿性血管畸形引起的蛛网膜下腔出血较为罕见。我们遇到了两例以血管母细胞型脑膜瘤和血管错构瘤引起的蛛网膜下腔出血为首发症状的病例。病例1:一名48岁女性,于1972年2月10日出现严重头痛和呕吐,随后逐渐嗜睡。腰椎穿刺显示脑脊液中度出血。发病后第五天,她入住我院。入院时,她表现出定向障碍和近期记忆障碍。轻度失语和失认。眼科检查发现右侧同向性下象限偏盲。颈动脉血管造影显示大脑前动脉轻度向右侧方形移位,大脑中动脉抬高,毛细血管期枕叶区域有均匀的肿瘤染色。发现一个核桃大小的肿瘤侵犯左侧外侧窦中部并与小脑幕紧密粘连。肿瘤后方有脑内血肿。将肿瘤、小脑幕和外侧窦整块切除,并吸出脑内血肿。组织学检查显示为血管母细胞型脑膜瘤。病例2:一名7岁男孩,于1972年9月17日出现严重突发头痛、颈部疼痛和呕吐,随后逐渐嗜睡。腰椎穿刺显示脑脊液出血。发病后第十天,他入住我院。他表现出意识模糊和烦躁不安。颈动脉血管造影显示胼周动脉迂曲,但未发现占位性病变。气脑造影显示一个球形充盈缺损突入右侧侧脑室前角。通过经脑室入路分块切除位于前角外侧壁的肿瘤。组织学检查显示为血管错构瘤。此外,我们还根据文献讨论了以蛛网膜下腔出血为首发症状的各种脑肿瘤、其发生率及出血机制。