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帕金森病中的一种特定转换缺陷:一致刺激-反应映射的逆向转换

A specific shifting deficit in Parkinson's disease: a reversal shift of consistent stimulus-response mappings.

作者信息

Hsieh S, Chuang Y Y, Hwang W J, Pai M C

机构信息

Department of Psychology, National Chung Cheng University, Taiwan, R.O.C.

出版信息

Percept Mot Skills. 1998 Dec;87(3 Pt 1):1107-19. doi: 10.2466/pms.1998.87.3.1107.

DOI:10.2466/pms.1998.87.3.1107
PMID:9885083
Abstract

Two experiments were designed to investigate effects of cueing upon aptitude for shifting by patients with Parkinson's disease. Subjects executed in alternation two different components of a task set over successive items in a list. We compared the costs of shifting when the stimulus ensemble remained constant from trial to trial ("uniform" lists), with the case in which a change of stimulus ensemble cued each shift of task ("mixed" lists). Shift costs with mixed lists were significantly smaller than those with uniform lists (Exp. 1, ns = 12). This suggests that patients with Parkinson's disease can benefit from cues about the stimulus ensemble in performing tasks. Patients' shifting performance was different from that of controls only in a reversal-shift condition of the previously consistent stimulus-response mappings (Exp. 2, ns = 12). This result suggests that patients with Parkinson's disease suffer from a specific but not a general deficit in ability to shift.

摘要

设计了两项实验来研究提示对帕金森病患者转换能力的影响。受试者在列表中的连续项目上交替执行任务集的两个不同组成部分。我们比较了每次试验刺激集合保持不变时(“统一”列表)的转换成本,以及每次任务转换都有刺激集合变化提示时(“混合”列表)的情况。混合列表的转换成本显著低于统一列表(实验1,n = 12)。这表明帕金森病患者在执行任务时可以从关于刺激集合的提示中受益。仅在先前一致的刺激 - 反应映射的反转转换条件下,患者的转换表现与对照组不同(实验2,n = 12)。这一结果表明帕金森病患者存在特定而非普遍的转换能力缺陷。

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