Asieh S, Lee C Y, Hwang W J, Tsai J J
Department of Psychology, National Chung Cheng University, Taiwan, R.O.C.
Percept Mot Skills. 1997 Dec;85(3 Pt 2):1315-25. doi: 10.2466/pms.1997.85.3f.1315.
Research into Parkinson's disease has made much use of the precuing paradigm developed by Posner to examine patients' ability to shift visuospatial attention. The majority of studies indicate that patients with Parkinson's disease have significantly reduced shift costs when compared with normal controls. This reduction in costs is ascribed to abnormal maintenance of attention resulting from Parkinson's disease. We know that visual attention is not directed to spatial locations alone but that it may also be directed to object representations. To date, however, it has not been clear whether the reduced shift costs apparent in Parkinson's disease patients are evident only on spatial locations or on both spatial locations and object representations. Therefore, in the current study we have adopted a new technique with a view to studying both location-based and object-based attentional components within the same paradigm. Our results with 17 patients with Parkinson's disease suggest, at least in the early stages, patients do not show deficits in maintenance of attention to the miscued source of stimulation as reflected in their normal magnitude of cuing effect related to shifting between locations and between objects. 14 normal persons were control subjects.
帕金森病的研究大量运用了波斯纳开发的预线索范式，以检验患者转移视觉空间注意力的能力。大多数研究表明，与正常对照组相比，帕金森病患者的转移成本显著降低。成本的降低归因于帕金森病导致的注意力维持异常。我们知道，视觉注意力并非仅指向空间位置，还可能指向物体表征。然而，迄今为止尚不清楚，帕金森病患者中明显降低的转移成本是否仅在空间位置上明显，还是在空间位置和物体表征两者上都明显。因此，在当前研究中，我们采用了一种新技术，以便在同一范式中研究基于位置和基于物体的注意力成分。我们对17名帕金森病患者的研究结果表明，至少在早期阶段，患者在维持对错误提示的刺激源的注意力方面没有表现出缺陷，这体现在他们与位置之间以及物体之间转移相关的线索效应大小正常。14名正常人作为对照对象。
