Zhu J M, Smith I C
Institute for Biodiagnostics, National Research Council of Canada, 435 Ellice Avenue, Winnipeg, MB, R3B 1Y6, Canada.
J Magn Reson. 1999 Jan;136(1):1-5. doi: 10.1006/jmre.1998.1621.
Spectral localization using the stimulated-echo acquisition mode (STEAM) is one of the most popular methods in volume-localized in vivo NMR spectroscopy. The localized volume signal is generated via stimulated echoes from spins excited by three 90 degrees RF pulses, and the conventional STEAM sequence detects the stimulated-echo signal. From an analysis of the STEAM pulse sequence using the coherence transfer pathway formalism, stimulated anti-echoes are also formed by the same pulse sequence, which constitute the other half of the localized signal in the STEAM experiment. A new scheme of pulsed field gradients for the selection of stimulated anti-echoes was proposed, and localized spectroscopy in the stimulated anti-echo selection mode was achieved on a phantom and from in vivo rat brain.
使用受激回波采集模式（STEAM）的谱定位是体内核磁共振波谱体积定位中最流行的方法之一。局部体积信号是由三个90度射频脉冲激发的自旋产生的受激回波产生的，传统的STEAM序列检测受激回波信号。通过使用相干转移路径形式对STEAM脉冲序列进行分析，相同的脉冲序列也会形成受激反回波，这构成了STEAM实验中局部信号的另一半。提出了一种用于选择受激反回波的脉冲场梯度新方案，并在体模和大鼠活体脑上实现了受激反回波选择模式下的局部波谱分析。
