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乳腺癌。与用于甲状腺功能减退的甲状腺补充剂的关系。

Breast cancer. Relationship to thyroid supplements for hypothyroidism.

作者信息

Kapdi C C, Wolfe J N

出版信息

JAMA. 1976 Sep 6;236(10):1124-7. doi: 10.1001/jama.236.10.1124.

Abstract

This study was undertaken to determine the relationship between thyroid supplements and breast cancer. The incidence of breast cancer among the patients who received thyroid supplements was 12.13%, while in the control group it was 6.2%. The incidence rate of breast cancer was 10%, 9.42%, and 19.48% among patients who received thyroid supplements for one to five, 5 to 15, and for more than 15 years, respectively. The incidence of breast cancer among nulliparous women who received thyroid supplements was 33%, while in the nulliparous women without thyroid supplements the incidence was only 9.25%. Even in a specific age group, the incidence rate of breast cancer was higher among patients receiving thyroid supplements, when compared to the control patients in the same age group.

摘要

本研究旨在确定甲状腺补充剂与乳腺癌之间的关系。接受甲状腺补充剂的患者中乳腺癌的发病率为12.13%,而对照组为6.2%。接受甲状腺补充剂1至5年、5至15年以及超过15年的患者中乳腺癌的发病率分别为10%、9.42%和19.48%。接受甲状腺补充剂的未生育女性中乳腺癌的发病率为33%,而未接受甲状腺补充剂的未生育女性中发病率仅为9.25%。即使在特定年龄组中,与同年龄组的对照患者相比,接受甲状腺补充剂的患者中乳腺癌的发病率也更高。

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