胚胎不对称性：左侧拥有所有最优良的基因。

Embryonic asymmetry: the left side gets all the best genes.

作者信息

King T, Brown N A

机构信息

Department of Anatomy and Developmental Biology, St George's Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK.

出版信息

Curr Biol. 1999 Jan 14;9(1):R18-22. doi: 10.1016/s0960-9822(99)80036-0.

DOI:10.1016/s0960-9822(99)80036-0

PMID:9889116

Abstract

The origin of left-right developmental asymmetry is a continuing puzzle, but some recent results provide new insights into the steps leading to organ asymmetry - implicating the homeobox protein Pitz-2 in one key step - and others support a model of symmetry-breaking that involves the chirality of microtubules.

摘要

左右发育不对称的起源一直是个谜，但最近的一些研究结果为导致器官不对称的步骤提供了新的见解——其中一个关键步骤涉及同源框蛋白Pitz-2——其他研究结果则支持一种涉及微管手性的对称性破缺模型。