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[嘌呤的吸收研究。第2部分。使用扩散装置的体外实验(作者译)]

[Absorption studies with purines. Part 2. In vitro experiments with a diffusion apparatus (author's transl)].

作者信息

Heppt-Becker I, Schunack W

出版信息

Arzneimittelforschung. 1976 Apr;26(4):473-6.

PMID:989000
Abstract

Various purines were investigated with the Desaga Resomat II, their diffusion speed constants calculated according to Stricker and compared with one another. The drugs investigated showed a proportinal relationship between diffusion speed and lipoid solubility. The effect of different membranes on the absorption experiments, with and without applied alternating pressure, was investigated. The results from the Sartorius Absorption Model and the Desaga Resomat II were compared.

摘要

使用德萨加Resomat II对各种嘌呤进行了研究,根据施特里克方法计算了它们的扩散速度常数并相互比较。所研究的药物在扩散速度和类脂溶解度之间呈现出比例关系。研究了不同膜对有无施加交变压力的吸收实验的影响。比较了赛多利斯吸收模型和德萨加Resomat II的结果。

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