惠普尔病

Whipple's disease.

作者信息

Ramaiah C, Boynton R F

机构信息

Division of Gastroenterology and Hepatology, Allegheny University of the Health Sciences, Philadelphia, Pennsylvania, USA.

出版信息

Gastroenterol Clin North Am. 1998 Sep;27(3):683-95, vii. doi: 10.1016/s0889-8553(05)70026-1.

DOI:10.1016/s0889-8553(05)70026-1

PMID:9891703

Abstract

Whipple's disease is a chronic, multisystem disease that is caused by Tropheryma whippelii infection. More information is now known about this unusual infectious process, which was once considered uniformly fatal. Immunologic, diagnostic, and therapeutic advancements are reviewed in this article. Hopefully, future advances in the basic and clinical sciences will lead to a more rapid diagnosis, more complete understanding of the effects of infection, improved therapy, and better clinical outcome.

摘要

惠普尔病是一种由惠普尔嗜组织菌感染引起的慢性多系统疾病。现在人们对这个曾经被认为无一例外会致命的不寻常感染过程有了更多了解。本文对免疫、诊断和治疗方面的进展进行了综述。希望基础科学和临床科学未来的进展将带来更快速的诊断、对感染影响更全面的理解、改进的治疗方法以及更好的临床结果。