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[成人心肌病的超声心动图检查]

[The echocardiographic examination in adult cardiomyopathy].

作者信息

Dubourg O, Pellerin D, Coisne D, Beauvais F, Jondeau G, Bourdarias J P

机构信息

Hôpital Ambroise-Paré, Boulogne.

出版信息

Arch Mal Coeur Vaiss. 1998 Dec;91(12 Suppl):35-42.

PMID:9891820
Abstract

Echocardiography allows distinction between the diastolic dysfunction of hypertrophic or restrictive cardiomyopathies and the systolic dysfunction of dilated cardiomyopathy. The diagnosis and prognosis may be deduced from echocardiographic parameters. In hypertrophic cardiomyopathy systolic function is normal and there is asymmetric left ventricular hypertrophy (> 13 mm) associated with a reduced diastolic dimension and atrial dilatation resulting from diastolic dysfunction. The prognosis could be related to the severity of left ventricular hypertrophy; right ventricular hypertrophy is uncommon and its severity seems to be related to that of left ventricular hypertrophy. Restrictive cardiomyopathies are less common and amyloidosis is the commonest cause. Symmetric hypertrophy with reduced diastolic dimensions is observed; right ventricular involvement occurs in about 30% of cases. The prognosis seems to be related to the degree of parietal infiltration and, at advanced stages, systolic function is abnormal (fractional shortening < 20% with a left ventricular diastolic dimension > or = 55 mm) and rapidly fatal. Dilated cardiomyopathy is diagnosed when wall thickness is normal but left ventricular diastolic dimensions > 27 mm/m2 and ejection fraction < 45%. Right and left ventricular dimensions of the same size, left ventricular diastolic dimensions > 70 mm and left ventricular ejection fractions < 20% are poor prognostic indicators.

摘要

超声心动图能够区分肥厚型或限制型心肌病的舒张功能障碍与扩张型心肌病的收缩功能障碍。诊断和预后可从超声心动图参数推断得出。在肥厚型心肌病中,收缩功能正常,存在不对称性左心室肥厚(>13毫米),伴有舒张期内径减小以及舒张功能障碍导致的心房扩大。预后可能与左心室肥厚的严重程度有关;右心室肥厚并不常见,其严重程度似乎与左心室肥厚相关。限制型心肌病较为少见,淀粉样变性是最常见的病因。可见对称性肥厚且舒张期内径减小;约30%的病例会出现右心室受累。预后似乎与心肌浸润程度有关,在疾病晚期,收缩功能异常(左心室舒张期内径≥55毫米时,缩短分数<20%)且病情进展迅速可致命。当室壁厚度正常但左心室舒张期内径>27毫米/平方米且射血分数<45%时,可诊断为扩张型心肌病。左右心室大小相同、左心室舒张期内径>70毫米以及左心室射血分数<20%是预后不良的指标。

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