Gandolfini M P, Lefrançois A M, Pannier-Moreau I, Guiomard A
Service de cardiologie, hôpital Max Fourestier, Nanterre.
Arch Mal Coeur Vaiss. 1998 Dec;91(12):1513-8.
The authors report an original case of the association of three pathologies: pheochromocytoma, hyperthyroidism and cardiomyopathy with left ventricular outflow tract obstruction. This type of cardiac disease has occasionally been described in cases of pheochromocytoma and are usually induced by the endocrine disturbance because they regress with treatment of the pheochromocytoma. The associated hyperthyroidism observed in this case is very rare and may have increased the left ventricular pressure gradient. Medical treatment before surgery of the pheochromocytoma was unusual in that a triple therapy was used including betablockers, classically contra-indicated in pheochromocytoma alone. In this case, it provided excellent control of the blood pressure and decreased the left ventricular obstruction during the perioperative period.
嗜铬细胞瘤、甲状腺功能亢进和伴有左心室流出道梗阻的心肌病。这种类型的心脏病在嗜铬细胞瘤病例中偶尔有描述，通常由内分泌紊乱诱发，因为它们会随着嗜铬细胞瘤的治疗而消退。该病例中观察到的相关甲状腺功能亢进非常罕见，可能增加了左心室压力梯度。嗜铬细胞瘤术前的药物治疗不同寻常，因为使用了三联疗法，其中包括β受体阻滞剂，而β受体阻滞剂单独用于嗜铬细胞瘤时通常是禁忌的。在该病例中，它对血压提供了良好的控制，并在围手术期减轻了左心室梗阻。
