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鼓励使用产前糖皮质激素疗法促进胎儿成熟的方法:一项随机对照试验。

Methods to encourage the use of antenatal corticosteroid therapy for fetal maturation: a randomized controlled trial.

作者信息

Leviton L C, Goldenberg R L, Baker C S, Schwartz R M, Freda M C, Fish L J, Cliver S P, Rouse D J, Chazotte C, Merkatz I R, Raczynski J M

机构信息

Department of Health Behavior, School of Public Health, University of Alabama at Birmingham, 35294-0033, USA.

出版信息

JAMA. 1999 Jan 6;281(1):46-52. doi: 10.1001/jama.281.1.46.

Abstract

CONTEXT

Antenatal corticosteroids for fetal maturation have been underused, despite evidence for their benefits in cases of preterm birth.

OBJECTIVE

To evaluate dissemination strategies aimed at increasing appropriate use of this therapy.

DESIGN AND SETTING

Twenty-seven tertiary care institutions were randomly assigned to either usual dissemination of practice recommendations (n = 14) or usual dissemination plus an active, focused dissemination effort (n = 13).

SUBJECTS

Obstetricians and their preterm delivery cases at participating hospitals.

INTERVENTION

Recommendations by a National Institutes of Health (NIH) Consensus Conference held in late February-early March 1994 were disseminated in early May 1994. Usual dissemination was publication of the recommendations and endorsement by the American College of Obstetricians and Gynecologists. Active dissemination was a year-long educational effort led by an influential physician and a nurse coordinator at each facility, consisting of grand rounds, a chart reminder system, group discussion of case scenarios, monitoring, and feedback.

MAIN OUTCOME MEASURE

Use or nonuse of antenatal corticosteroids was abstracted from medical records of eligible women delivering at the participating hospitals in the 12 months immediately prior to release of the NIH recommendations (average number of records abstracted, 130) and in the 12 months following their release (average number of records abstracted, 122).

RESULTS

Active dissemination significantly increased the odds of corticosteroid use after the conference. Use increased from 33.0% of eligible patients receiving corticosteroids to 57.6%, or by 75% over baseline, in usual dissemination hospitals. Use increased from 32.9% to 68.3%, oran 108% increase, in active dissemination hospitals. Gestational age and maternal diagnosis affected use of the therapy in complex ways.

CONCLUSION

An active, focused dissemination effort increased the effectiveness of usual dissemination methods when combined with key principles to change physician practices.

摘要

背景

尽管有证据表明产前使用皮质类固醇对胎儿成熟有益,但这种疗法的使用一直不足。

目的

评估旨在增加这种疗法合理使用的传播策略。

设计与地点

27家三级医疗机构被随机分为两组,一组采用常规方式传播实践建议(n = 14),另一组采用常规传播方式加积极、有针对性的传播努力(n = 13)。

研究对象

参与医院的产科医生及其早产病例。

干预措施

1994年2月下旬至3月初举行的美国国立卫生研究院(NIH)共识会议的建议于1994年5月初进行传播。常规传播方式是发布这些建议并得到美国妇产科医师学会的认可。积极传播是由每个机构的一位有影响力的医生和一名护士协调员领导的为期一年的教育活动,包括大查房、图表提醒系统、病例情景小组讨论、监测和反馈。

主要观察指标

从参与医院在NIH建议发布前12个月(平均抽取记录数量为130份)和发布后12个月(平均抽取记录数量为122份)分娩的符合条件妇女的病历中提取是否使用产前皮质类固醇的信息。

结果

积极传播显著增加了会议后使用皮质类固醇的几率。在常规传播医院,使用皮质类固醇的合格患者比例从33.0%增加到57.6%,比基线增加了75%。在积极传播医院,使用比例从32.9%增加到68.3%,增加了108%。孕周和母亲诊断以复杂的方式影响该疗法的使用。

结论

当与改变医生行为的关键原则相结合时,积极、有针对性的传播努力提高了常规传播方法的有效性。

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