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Determination of continuous changes in the gel layer thickness of poly(ethylene oxide) and HPMC tablets undergoing hydration: a texture analysis study.

作者信息

Yang L, Johnson B, Fassihi R

机构信息

Department of Pharmaceutical Sciences, School of Pharmacy, Temple University, Philadelphia, Pennsylvania 19140, USA.

出版信息

Pharm Res. 1998 Dec;15(12):1902-6. doi: 10.1023/a:1011970409699.

DOI:10.1023/a:1011970409699
PMID:9892476
Abstract
摘要

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Determination of continuous changes in the gel layer thickness of poly(ethylene oxide) and HPMC tablets undergoing hydration: a texture analysis study.
Pharm Res. 1998 Dec;15(12):1902-6. doi: 10.1023/a:1011970409699.
2
The effect of wet granulation on the erosion behaviour of an HPMC-lactose tablet, used as a rate-controlling component in a pulsatile drug delivery capsule formulation.湿法制粒对羟丙甲纤维素-乳糖片侵蚀行为的影响，该片剂在脉冲式给药胶囊制剂中用作控速成分。
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Method to recover a lipophilic drug from hydroxypropyl methylcellulose matrix tablets.从羟丙基甲基纤维素基质片剂中回收亲脂性药物的方法。
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High molecular weight polyethylene oxides (PEOs) as an alternative to HPMC in controlled release dosage forms.高分子量聚环氧乙烷（PEOs）作为控释剂型中羟丙基甲基纤维素（HPMC）的替代品。
Int J Pharm. 2000 Feb 15;195(1-2):229-38. doi: 10.1016/s0378-5173(99)00402-0.
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[Description of the release of sodium ferulate from hydroxypropyl methylcellulose based matrix tablets in vitro].[阿魏酸钠从羟丙基甲基纤维素基骨架片中的体外释放特性描述]
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NMR microscopy of hydrating hydrophilic matrix pharmaceutical tablets.水合亲水性基质药物片剂的核磁共振显微镜检查
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Correlation between the viscoelastic properties of the gel layer of swollen HPMC matrix tablets and their in vitro drug release.膨胀 HPMC 基质片剂凝胶层的粘弹性性质与其体外药物释放的相关性。
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Swelling of hydroxypropyl methylcellulose matrix tablets. 2. Mechanistic study of the influence of formulation variables on matrix performance and drug release.羟丙基甲基纤维素骨架片的溶胀。2. 制剂变量对骨架性能和药物释放影响的机制研究。
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Influence of water soluble fillers in hydroxypropylmethylcellulose matrices on in vitro and in vivo drug release.羟丙基甲基纤维素基质中水溶性填充剂对药物体外及体内释放的影响
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Mechanisms of drug release in citrate buffered HPMC matrices.药物在柠檬酸盐缓冲羟丙基甲基纤维素基质中的释放机制。
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本文引用的文献

1
Complications in investigations of the swelling of hydrogel matrices due to the presence of trapped gas.由于存在截留气体而导致水凝胶基质肿胀研究中的并发症。
J Control Release. 1998 Mar 2;52(1-2):221-5. doi: 10.1016/s0168-3659(97)00217-4.
2
Application of a binary polymer system in drug release rate modulation. 1. Characterization of release mechanism.二元聚合物体系在药物释放速率调节中的应用。1. 释放机制的表征。
J Pharm Sci. 1997 Mar;86(3):316-22. doi: 10.1021/js960302s.
3
Swelling of hydroxypropyl methylcellulose matrix tablets. 1. Characterization of swelling using a novel optical imaging method.
制剂和工艺变量对含高剂量可溶性药物的胃滞留漂浮片的影响及实验设计方法
Pharmaceutics. 2018 Sep 17;10(3):161. doi: 10.3390/pharmaceutics10030161.
4
A novel approach in distinguishing between role of hydrodynamics and mechanical stresses similar to contraction forces of GI tract on drug release from modified release dosage forms.一种区分流体动力学和类似于胃肠道收缩力的机械应力对缓释剂型药物释放作用的新方法。
AAPS PharmSciTech. 2015 Apr;16(2):278-83. doi: 10.1208/s12249-014-0225-5. Epub 2014 Oct 2.
5
Inter-grade and inter-batch variability of sodium alginate used in alginate-based matrix tablets.藻酸盐基质片剂中使用的海藻酸钠的批间和批次间变异性。
AAPS PharmSciTech. 2014 Oct;15(5):1228-37. doi: 10.1208/s12249-014-0154-3. Epub 2014 Jun 3.
6
Release characteristics of quetiapine fumarate extended release tablets under biorelevant stress test conditions.富马酸喹硫平缓释片在生物相关应激条件下的释放特性。
AAPS PharmSciTech. 2014 Feb;15(1):230-6. doi: 10.1208/s12249-013-0050-2. Epub 2013 Dec 3.
7
Oral drug delivery systems comprising altered geometric configurations for controlled drug delivery.包含改变的几何配置的口腔药物传递系统用于控制药物释放。
Int J Mol Sci. 2012;13(1):18-43. doi: 10.3390/ijms13010018. Epub 2011 Dec 22.
8
Effect of drug solubility on polymer hydration and drug dissolution from polyethylene oxide (PEO) matrix tablets.药物溶解度对聚环氧乙烷（PEO）基质片剂中聚合物水化及药物溶出的影响。
AAPS PharmSciTech. 2008;9(2):437-43. doi: 10.1208/s12249-008-9060-x. Epub 2008 Mar 8.
羟丙基甲基纤维素基质片剂的溶胀。1. 使用新型光学成像方法对溶胀进行表征。
J Pharm Sci. 1996 Jul;85(7):725-31. doi: 10.1021/js950458c.
4
Structure and behavior in hydrophilic matrix sustained release dosage forms: 4. Studies of water mobility and diffusion coefficients in the gel layer of HPMC tablets using NMR imaging.亲水性基质缓释剂型的结构与行为：4. 使用核磁共振成像研究羟丙基甲基纤维素片凝胶层中的水迁移率和扩散系数
Pharm Res. 1996 Mar;13(3):376-80. doi: 10.1023/a:1016084224084.
5
Zero-order release kinetics from a self-correcting floatable asymmetric configuration drug delivery system.自校正可漂浮不对称构型药物递送系统的零级释放动力学
J Pharm Sci. 1996 Feb;85(2):170-3. doi: 10.1021/js950250r.
6
The relationship between the glass transition temperature and the water content of amorphous pharmaceutical solids.无定形药物固体的玻璃化转变温度与含水量之间的关系。
Pharm Res. 1994 Apr;11(4):471-7. doi: 10.1023/a:1018941810744.
7
Drug diffusion front movement is important in drug release control from swellable matrix tablets.药物扩散前沿移动对于从可溶胀性骨架片中控制药物释放很重要。
J Pharm Sci. 1995 Aug;84(8):991-7. doi: 10.1002/jps.2600840816.
8
Drug/polymer matrix swelling and dissolution.药物/聚合物基质的溶胀与溶解。
Pharm Res. 1988 Aug;5(8):488-94. doi: 10.1023/a:1015913207052.