Taghavy A, Penning J, Hoh E
Arzneimittelforschung. 1976;26(6):1125-6.
The method of simultaneous recording of visual-evoked response (1 occipit-vertex) and simple reaction time to periodic foveal visual stimuli of 1/" per sec was applied to 16 normal individuals. On two successive days the conditions were kept constant except for an independent variable, i.e., ethanol with an average peak of 1.32%; the range of 0.1% below the peak being examined. The amplitude of the component N2-P3 (120-170 msec after the stimuli) was depressed in all individuals. The latencies of N2 and P3 were increased concurrently. The latency of P3, for example, was increased by 10.7% (P less than or equal 0.01) and that of the means of simultaneously recorded reaction time by 14.8% (P less than or equal 0.01). The amount of the increase, however, showed no significant correlation between the two when using Spearman's correlation coefficient and t-test.
对16名正常个体采用同时记录视觉诱发电位(枕部-顶点)和对每秒1°的周期性中央凹视觉刺激的简单反应时间的方法。在连续两天里,除了一个自变量(即平均峰值为1.32%的乙醇,研究低于峰值0.1%的范围)外,其他条件保持不变。所有个体中N2-P3成分(刺激后120 - 170毫秒)的波幅均降低。N2和P3的潜伏期同时延长。例如,P3的潜伏期增加了10.7%(P≤0.01),同时记录的反应时间平均值的潜伏期增加了14.8%(P≤0.01)。然而,当使用斯皮尔曼相关系数和t检验时,两者增加量之间未显示出显著相关性。