HL-A8与对各种抗原的免疫反应。

HL-A8 and the immune response to various antigens.

作者信息

Scott B B, Cooke E M, Hambling M H, Rajah S M, Swinburne M L, Losowsky M S

出版信息

J Immunogenet. 1976 Jun;3(3):185-9. doi: 10.1111/j.1744-313x.1976.tb00571.x.

DOI:10.1111/j.1744-313x.1976.tb00571.x

Abstract

The possession of the histocompatibility antigen HL-A8 has been correlated with serum levels of antibodies to gluten and a variety of other dietary, viral, and bacterial antigens and autoantigens. The only significant correlation with HL-A8 was of raised levels of gluten antibody. Thus it seems that HL-A8 may be associated with an enhanced immune response specifically to gluten, and not with a generally enhanced immunological responsiveness as has been suggested.

摘要

组织相容性抗原HL - A8的存在与针对麸质以及多种其他饮食、病毒、细菌抗原和自身抗原的抗体血清水平相关。与HL - A8唯一显著相关的是麸质抗体水平升高。因此，似乎HL - A8可能与针对麸质的免疫反应增强有关，而不是如所暗示的那样与整体免疫反应性增强有关。