• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

共焦显微镜下角膜线性图像的鉴别诊断

Differential diagnosis of linear corneal images on confocal microscopy.

作者信息

Chiou A G, Kaufman S C, Beuerman R W, Ohta T, Kaufman H E

机构信息

Louisiana State University Eye Center, New Orleans 70112-2234, USA.

出版信息

Cornea. 1999 Jan;18(1):63-6.

PMID:9894939
Abstract

PURPOSE

This study aimed to detect corneal conditions presenting with linear images on white light confocal microscopy and to analyze their distinguishing characteristics.

METHODS

In 1996 and 1997, 153 eyes of 110 patients with various corneal conditions were examined. In vivo examination of the cornea was performed by using a white-light tandem scanning confocal microscope. Images were captured by using a video camera and stored on S-VHS video tapes. In this retrospective study, patient charts and confocal microscopic video records were reviewed. Conditions with linear images were looked for, and the images were analyzed and compared.

RESULTS

The only structures presenting as linear images on confocal microscopy in normal subjects consisted of corneal nerves. The following pathologic conditions also had linear images on confocal microscopy: corneal vascularization, mycotic keratitis, lattice corneal dystrophy, and posterior polymorphous dystrophy. Each condition could be identified based on its reflectivity, delineation, size, branching pattern, and location in the cornea.

CONCLUSION

Different corneal conditions present with linear images on confocal microscopy. Correct identification is critical to avoid misdiagnosis.

摘要

目的

本研究旨在检测在白光共聚焦显微镜下呈现线性图像的角膜病变情况,并分析其鉴别特征。

方法

1996年和1997年,对110例患有各种角膜病变的患者的153只眼睛进行了检查。使用白光串联扫描共聚焦显微镜对角膜进行活体检查。通过摄像机采集图像并存储在S - VHS录像带上。在这项回顾性研究中,查阅了患者病历和共聚焦显微镜视频记录。寻找呈现线性图像的病变情况,并对图像进行分析和比较。

结果

正常受试者在共聚焦显微镜下呈现为线性图像的唯一结构是角膜神经。以下病理状况在共聚焦显微镜下也有线性图像:角膜血管化、真菌性角膜炎、格子状角膜营养不良和后弹力层多形性营养不良。每种状况都可根据其反射率、轮廓、大小、分支模式以及在角膜中的位置来识别。

结论

不同的角膜病变在共聚焦显微镜下呈现线性图像。正确识别对于避免误诊至关重要。

相似文献

1
Differential diagnosis of linear corneal images on confocal microscopy.共焦显微镜下角膜线性图像的鉴别诊断
Cornea. 1999 Jan;18(1):63-6.
2
Epithelial basement membrane dystrophy: evaluation with the HRT II Rostock Cornea Module.上皮基底膜营养不良:使用HRT II罗斯托克角膜模块进行评估。
Ophthalmology. 2006 Aug;113(8):1301-8. doi: 10.1016/j.ophtha.2006.03.050.
3
Clinical corneal confocal microscopy.临床角膜共焦显微镜检查
Surv Ophthalmol. 2006 Sep-Oct;51(5):482-500. doi: 10.1016/j.survophthal.2006.06.010.
4
Corneal and conjunctival manifestations in Fabry disease: in vivo confocal microscopy study.法布里病的角膜和结膜表现:活体共聚焦显微镜研究
Am J Ophthalmol. 2006 Apr;141(4):709-18. doi: 10.1016/j.ajo.2005.11.053.
5
Clinical and microstructural analysis of patients with hyper-reflective corneal endothelial nuclei imaged by in vivo confocal microscopy.通过活体共聚焦显微镜成像的角膜内皮细胞核高反射患者的临床和微观结构分析。
Exp Eye Res. 2006 Apr;82(4):682-7. doi: 10.1016/j.exer.2005.09.006. Epub 2005 Dec 15.
6
Confocal microscopy of cystic disorders of the corneal epithelium.
Ophthalmology. 1998 Apr;105(4):631-6. doi: 10.1016/S0161-6420(98)94016-7.
7
Long-term microstructural changes following epikeratophakia: in vivo confocal microscopy study.表层角膜镜片术后的长期微观结构变化:活体共聚焦显微镜研究
J Cataract Refract Surg. 2008 Oct;34(10):1793-8. doi: 10.1016/j.jcrs.2008.04.053.
8
[Morphologic characteristics of cornea in Fuchs endothelial dystrophy observed by confocal microscopy].[共焦显微镜观察Fuchs内皮营养不良角膜的形态学特征]
Zhonghua Yan Ke Za Zhi. 2004 Jul;40(7):465-70.
9
Comparative anatomy of laboratory animal corneas with a new-generation high-resolution in vivo confocal microscope.使用新一代高分辨率活体共聚焦显微镜对实验动物角膜进行比较解剖学研究。
Curr Eye Res. 2006 Jun;31(6):501-9. doi: 10.1080/02713680600701513.
10
Confocal microscopy in ophthalmology.眼科中的共聚焦显微镜检查。
Am J Ophthalmol. 2009 Nov;148(5):639-46. doi: 10.1016/j.ajo.2009.06.022. Epub 2009 Aug 11.

引用本文的文献

1
In vivo Confocal Microscopy for Corneal and Ocular Surface Pathologies: A Comprehensive Review.用于角膜和眼表疾病的体内共聚焦显微镜检查:全面综述。
Clin Ophthalmol. 2025 Jun 7;19:1817-1834. doi: 10.2147/OPTH.S519705. eCollection 2025.
2
Prospective Study of the Diagnostic Accuracy of the In Vivo Laser Scanning Confocal Microscope for Severe Microbial Keratitis.体内激光扫描共聚焦显微镜对严重微生物性角膜炎诊断准确性的前瞻性研究
Ophthalmology. 2016 Nov;123(11):2285-2293. doi: 10.1016/j.ophtha.2016.07.009. Epub 2016 Aug 15.
3
Clinical applications of corneal confocal microscopy.
角膜共焦显微镜的临床应用
Clin Ophthalmol. 2008 Jun;2(2):435-45. doi: 10.2147/opth.s1490.
4
Corneal sensation after myopic and hyperopic LASIK: clinical and confocal microscopic study.近视和远视LASIK术后角膜感觉:临床与共焦显微镜研究
Br J Ophthalmol. 2005 May;89(5):580-5. doi: 10.1136/bjo.2004.046888.
5
Corneal wound healing after photorefractive keratectomy: a 3-year confocal microscopy study.准分子激光角膜切削术后角膜伤口愈合:一项为期3年的共聚焦显微镜研究。
Trans Am Ophthalmol Soc. 2003;101:293-333.
6
In vivo confocal microscopy of the human cornea.人角膜的体内共焦显微镜检查。
Br J Ophthalmol. 2003 Feb;87(2):225-36. doi: 10.1136/bjo.87.2.225.