Karim S M, Ratnam S S
Br J Obstet Gynaecol. 1976 Nov;83(11):885-9. doi: 10.1111/j.1471-0528.1976.tb00767.x.
A synthetic compound, 2a, 2b dihomo 15 (S) 15 methyl prostaglandin F 2 alpha methyl ester given 8-hourly by intramuscular injection was used to terminate pregnancies in 72 patients with a missed abortion, intrauterine fetal death, molar or anencephalic pregnancies. Treatment was successful in all cases. A 4 mg dose of loperamide given orally at 15 to 30 minutes before the injection of prostaglandin analogue prevented diarrhoea as a side effect.
一种合成化合物,即2a,2b - 二高 - 15(S) - 15 - 甲基前列腺素F2α甲酯,通过肌肉注射每8小时给药一次,用于终止72例稽留流产、宫内死胎、葡萄胎或无脑儿妊娠患者的妊娠。所有病例治疗均成功。在注射前列腺素类似物前15至30分钟口服4毫克洛哌丁胺可预防腹泻这一副作用。