Doyle P T, Briscoe C E
Br J Urol. 1976 Oct;48(5):329-35. doi: 10.1111/j.1464-410x.1976.tb06645.x.
The influence of sedative, anaesthetic and neuromuscular blocking drugs on diagnostic urethral pressure profiles and cystometrograms has been investigated. These agents have marked effects on the results obtained; in particular, the urethral pressure profile was raised by opiates and lowered by anaesthetic induction agents. Bladder capacity as measured by the cystometrogram was greatly increased by halothane. These findings indicate that urodynamic studies should be performed only on conscious unsedated patients.
已对镇静药、麻醉药和神经肌肉阻滞剂对诊断性尿道压力曲线和膀胱压力图的影响进行了研究。这些药物对所获得的结果有显著影响；特别是，阿片类药物使尿道压力曲线升高，而麻醉诱导剂使其降低。通过膀胱压力图测量的膀胱容量在氟烷作用下大幅增加。这些发现表明，尿动力学研究应仅在清醒且未使用镇静剂的患者身上进行。
