急性蝎源性胰腺炎病因的实验研究
Experimental studies on the aetiology of acute scorpion pancreatitis.
作者信息
Bartholomew C, McGeeney K F, Murphy J J, Fitzgerald O, Sankaran H
出版信息
Br J Surg. 1976 Oct;63(10):807-10. doi: 10.1002/bjs.1800631019.
Abstract
This study examined the action of the venom of the scorpion Tityus trintatis on the pancreas and gastrointestinal tract in anaesthetized dogs, on the isolated extracorporeal haemoperfused canine pancreas and on the isolated canine sphincter of Oddi. The venom induces exocrine secretion in both the isolated and intact pancreas and causes contraction of the isolated sphincter of Oddi. These results are discussed in relation to the pathogenesis of acute scorpion pancreatitis and possibly of some other forms of acute pancreatitis.
摘要
本研究考察了三带盾尾蝎毒液对麻醉犬的胰腺和胃肠道、离体体外血液灌注犬胰腺以及离体犬奥迪括约肌的作用。该毒液可诱导离体和完整胰腺的外分泌，还能引起离体奥迪括约肌收缩。结合急性蝎源性胰腺炎以及其他一些急性胰腺炎的发病机制对这些结果进行了讨论。
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