人类白细胞抗原A9和人类白细胞抗原B5与血栓闭塞性脉管炎的关联。
Association of HLA-A9 and HLA-B5 with Buerger's disease.
作者信息
McLoughlin G A, Helsby C R, Evans C C, Chapman D M
出版信息
Br Med J. 1976 Nov 13;2(6045):1165-6. doi: 10.1136/bmj.2.6045.1165.
Abstract
Eighteen patients who satisfied stringent criteria for the diagnosis of Buerger's disease, healthy controls, and patients with atherosclerosis were tested for various HLA antigens. The incidence of HLA-A9 and HLA-B5 was significantly greater among those with Buerger's disease. This finding supports the concept that Buerger's disease is a distinct clinicopathological condition.
摘要
对18名符合布加氏病严格诊断标准的患者、健康对照者以及动脉粥样硬化患者进行了多种HLA抗原检测。布加氏病患者中HLA - A9和HLA - B5的发生率显著更高。这一发现支持了布加氏病是一种独特的临床病理状况的概念。
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