Tepper M L
Blood-borne Pathogens Division, Health Canada, Ottawa, Ont., Canada.
Vaccine. 1998 Nov;16 Suppl:S23-6. doi: 10.1016/s0264-410x(98)00287-4.
Hepatitis B (HB) vaccines are safe and effective. To control HB infection at a population level, use of this vaccine in a routine immunization programme targeted at specific age groups has been recommended. Young adolescents (10 to 13 yr of age) are a group which may well be considered for such a programme, especially if school-based. This paper outlines some of the rationale, advantages and disadvantages of targeting this age group for HB vaccine as well as providing some recommendations regarding operational matters related to such a programme.
乙型肝炎（HB）疫苗安全有效。为在人群层面控制HB感染，已建议在针对特定年龄组的常规免疫规划中使用该疫苗。青少年（10至13岁）很可能是这类规划的目标群体，特别是如果以学校为基础开展。本文概述了将该年龄组作为HB疫苗目标群体的一些基本原理、优缺点，并就与该规划相关的操作事项提供了一些建议。
