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氟硝西泮自愿使用的患病率、模式及相关因素

Prevalence, patterns, and correlates of voluntary flunitrazepam Use.

作者信息

Rickert V I, Wiemann C M, Berenson A B

机构信息

Department of Obstetrics and Gynecology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-0587, USA.

出版信息

Pediatrics. 1999 Jan;103(1):E6. doi: 10.1542/peds.103.1.e6.

Abstract

OBJECTIVE

To determine prevalence, patterns, and correlates of voluntary flunitrazepam use in a sample of sexually active adolescent and young adult women 14 to 26 years of age.

DESIGN

Cross-sectional survey.

SETTING

University-based ambulatory reproductive health clinics.

PATIENTS OR OTHER PARTICIPANTS

There were 904 women self-identified as white, African-American, or Mexican-American.

INTERVENTIONS

None.

MAIN OUTCOME MEASURE

Lifetime, frequency, patterns, and physical effects of flunitrazepam use.

RESULTS

Lifetime use was reported by 5.9% (n = 53) of subjects, with frequency of use ranging from 1 to 40 times. Flunitrazepam was taken most often with alcohol (74%), and 49% took this substance with other illicit drugs. Logistic regression analyses controlling for age and race/ethnicity found that users were significantly more likely than were nonusers to report lifetime use of marijuana (odds ratio [OR] = 3.6) or LSD (OR = 5.2), having a peer or partner who used flunitrazepam (OR = 21.7), pressure to use flunitrazepam when out with friends (OR = 2.7), and a mother who had at least a high school education (OR = 2.6). Finally, 10% of voluntary users reported experiencing subsequent physical or sexual victimization.

CONCLUSIONS

Voluntary use of flunitrazepam is becoming a health concern to sexually active young women who reside in the southwestern United States. Young women who have used LSD or marijuana in the past or who have a peer or partner who used this drug appear to be at the greatest risk.

摘要

目的

确定14至26岁性活跃的青少年及年轻成年女性样本中氟硝西泮自愿使用的患病率、模式及相关因素。

设计

横断面调查。

地点

大学附属门诊生殖健康诊所。

患者或其他参与者

904名自我认定为白人、非裔美国人或墨西哥裔美国人的女性。

干预措施

无。

主要观察指标

氟硝西泮使用的终生情况、频率、模式及身体影响。

结果

5.9%(n = 53)的受试者报告有终生使用情况,使用频率从1次至40次不等。氟硝西泮最常与酒精一起服用(74%),49%的人将该药物与其他非法药物一起服用。在控制年龄和种族/族裔的逻辑回归分析中发现,使用者比非使用者更有可能报告终生使用大麻(优势比[OR]=3.6)或麦角酸二乙酰胺(LSD,OR = 5.2),有使用氟硝西泮的同伴或伴侣(OR = 21.7),与朋友外出时有使用氟硝西泮的压力(OR = 2.7),以及母亲至少受过高中教育(OR = 2.6)。最后,10%的自愿使用者报告随后经历过身体或性方面的受害情况。

结论

在美国西南部,氟硝西泮的自愿使用正成为性活跃年轻女性的一个健康问题。过去使用过LSD或大麻,或有使用该药物的同伴或伴侣的年轻女性似乎风险最大。

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