一种求解结合平衡“n×m”情况的简单算法。

Experientia. 1976 Nov 15;32(11):1487-8. doi: 10.1007/BF01937452.

Accurate estimates of the equilibrium concentrations in the non-interactive reaction of several ligands with several classes of binding sites with univalent stoichiometry can be rapidly obtained by a simple method of successive approximations on a programmable desk calculator.

通过在可编程台式计算器上进行简单的逐次逼近法，能够快速获得几种配体与几类具有单价化学计量关系的结合位点发生非相互作用反应时平衡浓度的准确估计值。