Süer S, Baloğlu H, Güngör Z, Sönmez H, Kökoğlu E
Department of Biochemistry, Cerrahpaşa Medical Faculty, University of Istanbul, Turkey.
Cancer Biochem Biophys. 1998 Jun;16(1-2):63-70.
Our findings indicate that sialic acid and fibronectin levels in breast tumors are higher than those in normal tissues. The mean tissue fibronectin and sialic acid concentrations for patients with breast cancer were 30.90 +/- 9.68 microg/mg protein and 21.60 +/- 9.35 microg/mg protein, respectively, and for normal controls were 12.47 +/- 5.69 microg/mg protein, respectively. Tissue fibronectin and sialic acid can be important markers for human breast cancer.
我们的研究结果表明,乳腺肿瘤中的唾液酸和纤连蛋白水平高于正常组织。乳腺癌患者的组织纤连蛋白和唾液酸平均浓度分别为30.90±9.68微克/毫克蛋白质和21.60±9.35微克/毫克蛋白质,而正常对照组分别为12.47±5.69微克/毫克蛋白质。组织纤连蛋白和唾液酸可能是人类乳腺癌的重要标志物。