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[在肠黏膜物质作用下β-胡萝卜素及一些β-阿朴胡萝卜素类的转化]

[Conversion of beta-carotene and some beta-apocarotinoids under the effect of substances from the intestinal mucosa].

作者信息

Gessler N N, Dmitrovskiĭ A A, Gomboeva S B, Bykhovskiĭ V Ia

机构信息

Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow, Russia.

出版信息

Prikl Biokhim Mikrobiol. 1998 Nov-Dec;34(6):645-9.

PMID:9929894
Abstract

Products of cleavage of beta-carotene and certain apocarotenoids (beta-apo-4', 8', 10', and 12'-carotenols and citranaxanthol) were studied, and the dynamics of their generation in the presence of an enzyme preparation isolated from rabbit intestinal mucosa was determined. The data suggest that metabolism of beta-apocarotenols involves the production of retinal and beta-apo-14'-carotenal mediated by enzymes different from beta-carotene-15,15'-dioxygenase, which converts beta-carotene to retinal. A scheme of metabolic conversion of beta-carotene is discussed.

摘要

研究了β-胡萝卜素和某些类胡萝卜素裂解产物(β-阿朴-4'、8'、10'和12'-胡萝卜醇以及柠黄质),并测定了在从兔肠黏膜分离的酶制剂存在下它们的生成动力学。数据表明,β-阿朴胡萝卜醇的代谢涉及由不同于将β-胡萝卜素转化为视黄醛的β-胡萝卜素-15,15'-双加氧酶的酶介导的视黄醛和β-阿朴-14'-胡萝卜醛的产生。讨论了β-胡萝卜素的代谢转化方案。

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