Correlation between the concentration of isoleucine transfer RNA and the isoleucine content of hemoglobin in rabbit and sheep reticulocytes.

A correlation has been found between the concentration of isoleucine tRNA in reticulocytes and isoleucine content of rabbit and sheep hemoglobins: in rabbit reticulocytes, which synthesize a hemoglobin containing 8 residues of isoleucine per molecule, the isoleucine accepting activity is more than twice as high as in sheep reticulocytes, which produce a hemoglobin devoid of isoleucine.