Mayenburg J V, Vogt H J, Ziegelmayer G
Hautarzt. 1976 Sep;27(9):426-31.
Investigations of twins can contribute in the investigation of hereditary factors participating in the etiopathogenesis of vitiligo. A 28-year-old pair of male twins are presented, whose monovularity was conclusively proved by a comparison of morphological and serological features. Vitiligo developed as a concordant feature at the age of 13 and 22 years respectively. It is noticeable that there was a good concordance of the localisation of the vitiligo in both brothers. This concordance is most probably explained by genetic fixation of the disease, leading to the manifestation of vitiligo. Multifactoral heredity with threshold is discussed.
对双胞胎的研究有助于调查参与白癜风发病机制的遗传因素。本文报告了一对28岁的男性双胞胎，通过形态学和血清学特征比较最终证实他们为单卵双胞胎。白癜风分别在他们13岁和22岁时作为一种一致的特征出现。值得注意的是，两兄弟白癜风的发病部位有很好的一致性。这种一致性很可能是由该疾病的遗传固定性所解释的，从而导致了白癜风的表现。文中讨论了多因素阈值遗传。
