两种测量钙吸收分数方法的比较研究：正常个体及钙代谢各种紊乱患者的结果

A comparative study of two methods of measurement of fractional calcium absorption: results in normal individuals and patients with various disturbances of calcium metabolism.

作者信息

Juttmann J R, Ruis A M, Hagenouw-Taal J C, Lockefeer J H, Birkenhäger J C

出版信息

Eur J Clin Invest. 1978 Jun;8(3):137-42. doi: 10.1111/j.1365-2362.1978.tb00826.x.

DOI:10.1111/j.1365-2362.1978.tb00826.x

Abstract

Two methods of measurement of fractional calcium absorption have been compared in the same individuals. There is a significant correlation between fractional 47Ca absorption as measured with a blood counting method and with an external counting method after intravenous and oral administration of 47Ca (P less than 0.001). Two varieties of the external counting method, namely with intervals of 2 h and 7 days between the i.v. and oral doses, have been compared. In a group of twenty-one patients with chronic renal failure (not on haemodialysis), 47Ca absorption as measured by external counting was significantly lower than in the control group (P less than 0.001). When put on a dialysis programme a group of six patients showed a significant increase of the fractional 47Ca absorption (P less than 0.01).

摘要

在同一批个体中比较了两种测量钙吸收分数的方法。静脉注射和口服⁴⁷Ca后，用血细胞计数法和外部计数法测量的⁴⁷Ca吸收分数之间存在显著相关性（P<0.001）。比较了外部计数法的两种变体，即静脉注射和口服剂量之间间隔2小时和7天的情况。在一组21例慢性肾衰竭患者（未进行血液透析）中，通过外部计数测量的⁴⁷Ca吸收明显低于对照组（P<0.001）。一组6例患者开始透析治疗后，⁴⁷Ca吸收分数显著增加（P<0.01）。