Whitehouse G H, Griffiths G J
J Can Assoc Radiol. 1976 Dec;27(4):290-7.
Twenty-six patients with Ewing's tumor were studied. The spine was involved in eleven patients; the clinical and roentgenologic features of these are described. Four patients had primary Ewing's tumor of the spine; one showed uniform sclerosis of a single vertebra, a hitherto unreported finding. Two showed bone destruction; one showed no bone change on plain radiographs but there was complete obstruction on myelography. Two developed spinal metastases and died shortly afterwards. One patient is alive and well eight and a half years later. Seven patients had metastases to the spine from a non-spinal Ewing's tumor. All had neurologic complications. Plain radiographs showed no bone change in five; however, a paraspinal mass or an extra-dural mass shown on myelography, were relatively common. The mean survival time following spinal involvement was four months (range 1-12 months). No correlation was evident between the site of the primary lesion, the method of treatment, and the development of spinal metastases.
对26例尤因肉瘤患者进行了研究。11例患者脊柱受累;描述了这些患者的临床和X线特征。4例患者为原发性脊柱尤因肉瘤;1例表现为单个椎体均匀硬化,这是一个迄今未报告的发现。2例表现为骨质破坏;1例平片未见骨质改变,但脊髓造影显示完全梗阻。2例发生脊柱转移,随后不久死亡。1例患者在8年半后仍存活且状况良好。7例患者为非脊柱尤因肉瘤转移至脊柱。所有患者均有神经并发症。平片显示5例无骨质改变;然而,脊髓造影显示的椎旁肿块或硬膜外肿块相对常见。脊柱受累后的平均生存时间为4个月(范围1 - 12个月)。原发灶部位、治疗方法与脊柱转移的发生之间无明显相关性。