准分子原位角膜磨镶术后的角膜铁沉积
Corneal iron deposits after laser in situ keratomileusis.
作者信息
Vongthongsri A, Chuck R S, Pepose J S
机构信息
Department of Ophthalmology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
出版信息
Am J Ophthalmol. 1999 Jan;127(1):85-6. doi: 10.1016/s0002-9394(98)00301-8.
PURPOSE
To report the occurrence and features of corneal iron line deposition after laser in situ keratomileusis (LASIK).
METHODS
We evaluated 83 eyes undergoing LASIK. Corneal iron line deposition was analyzed with respect to preoperative spherical equivalent, attempted correction, and postoperative time interval.
RESULTS
Thirty-five (42.2%) of 83 eyes displayed a distinctive brown-colored corneal iron line of variable density in a ring or patch configuration near the margin of the ablated zone in the overlying corneal flap epithelium. The appearance of this iron line correlated positively with time after surgery (>3 months) and preoperative spherical equivalent (>-4.5 diopters).
CONCLUSIONS
Corneal iron line deposition in a ring or patch can be associated with previous LASIK surgery. This iron deposition within the margin of the ablated zone may offer insights into the dynamics of epithelial cell hyperplasia as well as basal cell proliferation, differentiation, and migration after LASIK.
目的
报告准分子原位角膜磨镶术（LASIK）后角膜铁线沉积的发生情况及特征。
方法
我们评估了83例行LASIK手术的眼睛。分析了角膜铁线沉积与术前等效球镜度、预期矫正量及术后时间间隔的关系。
结果
83只眼中有35只（42.2%）在覆盖的角膜瓣上皮消融区边缘附近出现了密度各异的独特棕色角膜铁线，呈环状或斑片状。这条铁线的出现与术后时间（>3个月）及术前等效球镜度（>-4.5屈光度）呈正相关。
结论
环状或斑片状角膜铁线沉积可能与既往LASIK手术有关。消融区边缘内的这种铁沉积可能有助于深入了解LASIK术后上皮细胞增生以及基底细胞增殖、分化和迁移的动态变化。
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