巨细胞病毒引起的免疫功能低下患者双侧急性视网膜坏死
Bilateral acute retinal necrosis caused by cytomegalovirus in an immunocompromised patient.
作者信息
Akpek E K, Kent C, Jakobiec F, Caliendo A M, Foster C S
机构信息
Department of Immunology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.
出版信息
Am J Ophthalmol. 1999 Jan;127(1):93-5. doi: 10.1016/s0002-9394(98)00250-5.
PURPOSE
To report a case of bilateral acute retinal necrosis caused by cytomegalovirus.
METHODS
A diagnostic vitrectomy was performed on a patient with non-Hodgkin lymphoma who presented with a bilateral, rapidly progressing necrotizing retinitis and uveitis.
RESULTS
Immunohistochemical studies and polymerase chain reaction disclosed cytomegalovirus as the cause of retinitis. The patient was treated with intravitreal and intravenous ganciclovir.
CONCLUSIONS
Although rare, cytomegalovirus may lead to an appearance identical to acute retinal necrosis and should be considered among the viral etiologies of this syndrome.
目的
报告1例由巨细胞病毒引起的双侧急性视网膜坏死病例。
方法
对1例非霍奇金淋巴瘤患者进行诊断性玻璃体切除术，该患者表现为双侧迅速进展的坏死性视网膜炎和葡萄膜炎。
结果
免疫组织化学研究和聚合酶链反应显示巨细胞病毒是视网膜炎的病因。患者接受了玻璃体内和静脉注射更昔洛韦治疗。
结论
尽管罕见，但巨细胞病毒可能导致与急性视网膜坏死相同的表现，在该综合征的病毒病因中应予以考虑。
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