使用鼻减充血剂后发生的前部缺血性视神经病变。
Anterior ischemic optic neuropathy following the use of a nasal decongestant.
作者信息
Fivgas G D, Newman N J
机构信息
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
出版信息
Am J Ophthalmol. 1999 Jan;127(1):104-6. doi: 10.1016/s0002-9394(98)00312-2.
PURPOSE
To report a case of sequential anterior ischemic optic neuropathy temporally related to the sequential use of a decongestant nasal spray.
METHODS
A 43-year-old woman was evaluated for sequential bilateral vision loss following the use of oxymetazoline nasal spray.
RESULTS
Thorough investigation of possible etiologies causing the bilateral anterior ischemic optic neuropathy was negative. Our patient had several predisposing risk factors for ischemic optic neuropathy, including diabetes mellitus, hypertension, and crowded optic nerve heads. Before each acute optic neuropathy, the patient used two to three puffs of oxymetazoline nasal spray.
CONCLUSION
Decongestants have been associated with ischemic and hemorrhagic vascular events. Vasoconstriction secondary to oxymetazoline use may precipitate anterior ischemic optic neuropathy.
目的
报告一例与连续使用减充血剂滴鼻剂时间相关的顺序性前部缺血性视神经病变病例。
方法
对一名43岁女性在使用羟甲唑啉滴鼻剂后出现顺序性双侧视力丧失进行评估。
结果
对导致双侧前部缺血性视神经病变的可能病因进行全面调查，结果为阴性。我们的患者有几个缺血性视神经病变的易感危险因素，包括糖尿病、高血压和视神经乳头拥挤。在每次急性视神经病变之前，患者使用两到三喷羟甲唑啉滴鼻剂。
结论
减充血剂与缺血性和出血性血管事件有关。使用羟甲唑啉引起的血管收缩可能会引发前部缺血性视神经病变。
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