Nagata H, Izumiyama T, Kamata K, Kono S, Yukimura Y
J Clin Endocrinol Metab. 1976 Nov;43(5):1153-6. doi: 10.1210/jcem-43-5-1153.
In an attempt to study an effect of cold on endocrine function in man, plasma thyroxine (T4), triiodothyronine (T3), TSH, and cortisol concentrations were studied in 24 healthy men who worked in a cold environment (4 to 6C) for 3 h for the culture of mushrooms and 56 healthy men who lived in cold environment in winter. For comparison, similar measurements were made on 47 university employees who lived in rooms with air-conditioning. In 24 adult men, acute exposure to cold for 3 h failed to affect plasma concentrations of T4, T3, and TSH. In 56 adult men, no significant difference was found in the concentrations of T4, TSH, and cortisol between summer and winter. However, plasma T3 concentration increased significantly in winter, suggesting seasonal variation of T3. In contrast, no such seasonal variation was found in 47 university employees who lived in rooms with air-conditioning.
为了研究寒冷对人体内分泌功能的影响，对24名在寒冷环境（4至6摄氏度）中从事3小时蘑菇种植工作的健康男性以及56名冬季生活在寒冷环境中的健康男性的血浆甲状腺素（T4）、三碘甲状腺原氨酸（T3）、促甲状腺激素（TSH）和皮质醇浓度进行了研究。作为对照，对47名在有空调房间居住的大学员工进行了类似测量。在24名成年男性中，急性暴露于寒冷环境3小时并未影响血浆T4、T3和TSH的浓度。在56名成年男性中，夏季和冬季的T4、TSH和皮质醇浓度未发现显著差异。然而，冬季血浆T3浓度显著升高，提示T3存在季节性变化。相比之下，在47名居住在有空调房间的大学员工中未发现此类季节性变化。
