van Rossum C T, van de Mheen H, Breteler M M, Grobbee D E, Mackenbach J P
Departments of Epidemiology, Biostatistics and Public Health, Erasmus University Rotterdam, Julius Center for Patient Oriented Research, Utrecht University, the Netherlands.
Stroke. 1999 Feb;30(2):357-62. doi: 10.1161/01.str.30.2.357.
We sought to assess the association between socioeconomic status and the risk of stroke among elderly women. Methods--The association between socioeconomic status and stroke emerged in cross-sectional and longitudinal data on 4274 female participants of the Rotterdam Study, a prospective, population-based, follow-up study in the Netherlands among older subjects.
A history of stroke was more common among women in lower socioeconomic strata. The same trend was observed for the relationship between the lowest socioeconomic groups and the incidence of stroke. Risk factors for stroke were not related to socioeconomic status in a consistent manner. Smoking, history of cardiovascular diseases, and overweight were more common in lower socioeconomic groups. However, socioeconomic differences in hypertension, antihypertensive drug use, prevalence of atrial fibrillation, and prevalence of left ventricular hypertrophy were not observed. The complex of established risk factors could only partly explain the association between socioeconomic status and stroke.
There is a strong association among elderly women between socioeconomic status and stroke. The association could only partly be explained by known risk factors. Our findings indicate that not only the actual risk profile but also risk factors earlier in life may be of importance.
我们试图评估老年女性社会经济地位与中风风险之间的关联。方法——社会经济地位与中风之间的关联出现在鹿特丹研究中4274名女性参与者的横断面和纵向数据中，该研究是荷兰一项针对老年受试者的前瞻性、基于人群的随访研究。
中风病史在社会经济地位较低的女性中更为常见。社会经济地位最低的群体与中风发病率之间的关系也呈现出相同趋势。中风的危险因素与社会经济地位之间没有一致的关联方式。吸烟、心血管疾病史和超重在社会经济地位较低的群体中更为常见。然而，在高血压、抗高血压药物使用、心房颤动患病率和左心室肥厚患病率方面未观察到社会经济差异。已确定的危险因素组合只能部分解释社会经济地位与中风之间的关联。
老年女性的社会经济地位与中风之间存在密切关联。这种关联只能部分由已知危险因素来解释。我们的研究结果表明，不仅实际的风险状况，而且生命早期的危险因素可能也很重要。
