Lammers F, Scheper T
Institute for Technical Chemistry, Hannover, Germany.
Adv Biochem Eng Biotechnol. 1999;64:35-67. doi: 10.1007/3-540-49811-7_2.
The application of enzyme thermistor devices for the continuous monitoring of enzymatic processes is described. Different hardware concepts are presented and discussed, practical results are also given. These devices were used to analyze the enantiomeric excess in biotransformation processes and for thermal immunoanalysis. In addition, the biosensors were applied for the monitoring and control of an L-ornithine producing process and for the application in hemodialysis monitoring. A review section discusses the use of thermal biosensors for monitoring biotechnological processes in general.
本文描述了酶热敏电阻装置在酶促过程连续监测中的应用。介绍并讨论了不同的硬件概念，还给出了实际结果。这些装置用于分析生物转化过程中的对映体过量以及进行热免疫分析。此外，生物传感器还应用于L-鸟氨酸生产过程的监测与控制以及血液透析监测。综述部分总体讨论了热生物传感器在生物技术过程监测中的应用。
