通过胎儿肾积水检查发现的原发性膀胱输尿管反流的特征。

Features of primary vesicoureteric reflux detected by investigation of foetal hydronephrosis.

作者信息

Oliveira E A, Diniz J S, Silva J M, Rabelo E A, Pontes A K, Souza M F

机构信息

Department of Paediatrics, Hospital das Clínicas, Federal University of Minas Gerais, Belo Horizonte, Brazil.

出版信息

Int Urol Nephrol. 1998;30(5):535-41. doi: 10.1007/BF02550541.

DOI:10.1007/BF02550541

PMID:9934793

Abstract

Primary vesicoureteric reflux (VUR) diagnosed on investigation of foetal hydronephrosis accounts for many antenatally detected uropathies. In order to study foetal VUR and its consequences, newborns with foetal hydronephrosis were investigated by ultrasound, micturating cystourethrogram and 99mTechnetium-dimercapto-succinic acid (DMSA), after beginning of chemoprophylaxis. Twenty-eight infants with VUR (bilateral in 15 cases) were identified giving a total 43 renal units for study. There was a predominance of males (86%), moderate/severe reflux (84%) and renal damage (51%). Presence of renal damage was correlated with the severity of reflux. VUR should be investigated in cases of foetal hydronephrosis and our results support that renal damage is frequently congenital and not secondary to urinary tract infection.

摘要

在胎儿肾积水检查中诊断出的原发性膀胱输尿管反流（VUR）是许多产前检测到的泌尿系统疾病的原因。为了研究胎儿VUR及其后果，在开始化学预防后，对患有胎儿肾积水的新生儿进行了超声、排尿性膀胱尿道造影和99m锝-二巯基丁二酸（DMSA）检查。确定了28例患有VUR的婴儿（15例为双侧），共43个肾单位用于研究。男性占优势（86%），中度/重度反流（84%）和肾损伤（51%）。肾损伤的存在与反流的严重程度相关。对于胎儿肾积水病例应进行VUR检查，我们的结果支持肾损伤通常是先天性的，而非继发于尿路感染。