家族性甲状旁腺功能亢进症：一例报告

Familial hyperparathyroidism: report of a case.

作者信息

Abe H, Tani T, Naito H, Mekata E, Sako H, Ioka J, Kodama M

机构信息

First Department of Surgery, Shiga University of Medical Science, Otsu, Japan.

出版信息

Surg Today. 1999;29(1):63-6. doi: 10.1007/BF02482972.

DOI:10.1007/BF02482972

PMID:9934834

Abstract

We report herein a case of familial primary hyperparathyroidism diagnosed in a 23-year-old woman who presented with hypercalcemia and urolithiasis. The parathyroid gland was removed, and pathological examination revealed chief cell adenoma. The proband's younger sister had undergone surgery for parathyroid adenoma at the age of 19, and her aunt had a history of urolithiasis with a high level of serum parathyroid hormone. We have not yet found evidence of any other endocrine disorders suggesting multiple endocrine neoplasia (MEN) type 1 in this pedigree.

摘要

我们在此报告一例23岁女性家族性原发性甲状旁腺功能亢进症，该患者表现为高钙血症和尿路结石。切除甲状旁腺后，病理检查显示为嗜酸细胞腺瘤。先证者的妹妹在19岁时接受了甲状旁腺腺瘤手术，她的姑姑有尿路结石病史且血清甲状旁腺激素水平较高。在这个家系中，我们尚未发现任何其他内分泌紊乱的证据提示1型多发性内分泌腺瘤病（MEN）。