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联合右肝和肝后下腔静脉切除并使用聚四氟乙烯移植物重建治疗原发性肝脏平滑肌肉瘤:病例报告

Combined right hepatic and retrohepatic caval resection with reconstruction using a polytetrafluoroethylene graft for primary leiomyosarcoma of the liver: report of case.

作者信息

Enoki T, Hayashi D, Inokuchi T, Okamura K, Takahashi T, Noshima S, Morita N, Esato K

机构信息

First Department of Surgery, Yamaguchi University, School of Medicine, Ube, Japan.

出版信息

Surg Today. 1999;29(1):67-70. doi: 10.1007/BF02482973.

Abstract

We present herein the case of a 53-year-old woman who underwent successful surgical treatment for a leiomyosarcoma of the liver that originated from the posterior hepatic segment and involved the retrohepatic inferior vena cava (IVC). A computed tomographic scan and magnetic resonance imaging demonstrated a large tumor, with rich vascularity, in the liver. The IVC was found to be occluded on these scans, which was confirmed by venacavography. The patient underwent a combined right hepatic and caval resection with reconstruction using an expanded polytetrafluoroethylene graft. The tumor consisted of spindle-shaped cells with cigar-shaped nuclei. It also had a moderate degree of cellularity and ten mitotic figures per ten high-power fields. Immunohistologically, desmin and alpha-smooth muscle actin were stained positive in the tumor cells, implying that the tumor was derived from smooth muscle cells. The patient is alive and well 15 months after her operation.

摘要

我们在此报告一例53岁女性患者,其肝脏平滑肌肉瘤起源于肝后段并累及肝后下腔静脉(IVC),接受手术治疗并获成功。计算机断层扫描和磁共振成像显示肝脏有一个大的、血管丰富的肿瘤。这些扫描发现下腔静脉闭塞,静脉造影证实了这一点。患者接受了右肝和下腔静脉联合切除,并使用膨体聚四氟乙烯移植物进行重建。肿瘤由梭形细胞组成,细胞核呈雪茄形。细胞密度中等,每十个高倍视野有十个有丝分裂象。免疫组织化学检查显示,肿瘤细胞中结蛋白和α-平滑肌肌动蛋白染色呈阳性,提示肿瘤起源于平滑肌细胞。患者术后15个月健在。

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