Lewis J W, Bryant V
J Helminthol. 1976 Sep;50(3):163-71. doi: 10.1017/s0022149x00027693.
Analyses of primary infections of Nematospiroides dubius in male and female laboratory mice show that on days 4--6 post-infection worms occupy up to 50% of the small intestine but as the age of the infection increases worm populations are highly aggregated in relation to the anterior sections of the small intestine. Individual worms are also shown to be aggregated with respect to each other. Between days 42 and 60 post-infection, although the pattern of distribution of N. dubius along the small intestine does not significantly change, survival of worms is influenced by both age and sex of ASH/CSI S.P.F. mice, reasons for which are discussed in the light of previous work on primary infections of N. dubius in other strains of laboratory mice.
对雄性和雌性实验小鼠体内杜氏丝状线虫原发性感染的分析表明,在感染后第4至6天,蠕虫占据小肠的比例高达50%,但随着感染时间的增加,蠕虫群体高度聚集在小肠前部。个体蠕虫之间也呈现聚集状态。在感染后第42至60天,尽管杜氏丝状线虫沿小肠的分布模式没有显著变化,但蠕虫的存活受到ASH/CSI无特定病原体小鼠的年龄和性别的影响,结合之前关于杜氏丝状线虫在其他品系实验小鼠中原发性感染的研究工作对其原因进行了讨论。