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移植后肾破裂

[Post-transplantation renal rupture].

作者信息

Pontones Moreno J L, Rodrigo Aliaga M, Monserrat Monfort J J, Guillén Navarro M, Sánchez Plumed J, Jiménez Cruz J F

机构信息

Servicio de Urología, Hospital Universitario La Fe, Valencia.

出版信息

Actas Urol Esp. 1998 Nov-Dec;22(10):840-5; discussion 846.

PMID:9949573
Abstract

INTRODUCTION

Renal allograft rupture in the transplanted patient represents a usually early postoperatory complication threatening graft and patient survival. Urgent management is often required.

MATERIAL AND METHODS

Renal transplanted patients which had rupture of the renal allograft have been reviewed retrospectively. Between February 1980 and June 1996 a total of 868 renal transplants were performed, and 21 (2.41%) suffered from allograft rupture. Diagnosis was based mainly on the symptoms, blood analysis to test hematocrit value, and ultrasounds.

RESULTS

Men age of the patients was 34 years old (21-49), 15 (71.4%) males and 6 (28.6%) females. Evolution was as follow: 4 patients underwent extracapsular nephrectomy due to non-functioning kidney; in 16 patients the graft could be preserved using different methods of renal corsetage (lyophilized human dura was applied in 8 cases, fascia lata in one, fascia lata and lyophilized human dura in 3 cases, and polyglycolic acid mesh in other 4 patients); and finally one patient was managed conservatively. There was no intra and post-operatory mortality. Four patients died lately of other causes not related to renal transplantation. Other 4 patients underwent chronic rejection and fail of the renal function. Two of these four patients have already received their second graft. A total of 13 patients have a good renal function (61.9%).

CONCLUSIONS

Early diagnosis of the renal allograft rupture must be the main objective in order to initiate as soon as possible therapeutic measures that firstly should be aimed to preserve the graft (medically or surgically). Nephrectomy must be reserved for renal allograft rupture secondary to venous thrombosis and other situations threatening life.

摘要

引言

移植患者的肾移植破裂通常是一种术后早期并发症,威胁着移植肾和患者的生存。通常需要紧急处理。

材料与方法

对肾移植破裂的患者进行了回顾性研究。1980年2月至1996年6月期间,共进行了868例肾移植,其中21例(2.41%)发生了移植肾破裂。诊断主要基于症状、检测血细胞比容值的血液分析以及超声检查。

结果

患者的平均年龄为34岁(21 - 49岁),男性15例(71.4%),女性6例(28.6%)。病情发展如下:4例因移植肾无功能而接受了包膜外肾切除术;16例患者通过不同的肾捆绑方法保留了移植肾(8例应用冻干人硬脑膜,1例应用阔筋膜,3例应用阔筋膜和冻干人硬脑膜,4例应用聚乙醇酸网);最后1例患者接受了保守治疗。术中及术后均无死亡病例。4例患者后期死于与肾移植无关的其他原因。另外4例发生慢性排斥反应且肾功能衰竭。这4例患者中有2例已接受了第二次移植。共有13例患者肾功能良好(61.9%)。

结论

肾移植破裂的早期诊断必须是主要目标,以便尽快启动治疗措施,首先应旨在保留移植肾(药物或手术治疗)。肾切除术必须保留用于因静脉血栓形成和其他威胁生命的情况导致的肾移植破裂。

相似文献

1
[Post-transplantation renal rupture].移植后肾破裂
Actas Urol Esp. 1998 Nov-Dec;22(10):840-5; discussion 846.
2
[The therapeutic management of the rupture of a kidney graft].
Arch Esp Urol. 1993 Nov;46(9):783-91.
3
Higher graft salvage rate in renal allograft rupture associated with acute tubular necrosis.
Transplant Proc. 2004 Dec;36(10):3016-8. doi: 10.1016/j.transproceed.2004.10.080.
4
Spontaneous renal allograft rupture without acute rejection.无急性排斥反应的自发性肾移植破裂
Acta Biomed. 2004 Aug;75(2):131-3.
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[Renal graft survival in patients with systemic lupus erythematosus].[系统性红斑狼疮患者的肾移植存活率]
Rev Invest Clin. 2002 Jan-Feb;54(1):21-8.
6
[Renal graft rupture].
Prog Urol. 2005 Apr;15(2):329-32.
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Renal allograft rupture caused by acute tubular necrosis.
Chir Ital. 2003 Sep-Oct;55(5):753-5.
8
Renal graft outcome in simultaneous kidney transplantation combined with other organs: experience of a single center.同期肾移植联合其他器官移植的肾移植结局:单中心经验
Transplant Proc. 2008 Dec;40(10):3424-7. doi: 10.1016/j.transproceed.2008.06.111.
9
[Operative management of spontaneous kidney transplant rupture. Personal experiences and literature review].
Chirurg. 1982 Jul;53(7):454-8.
10
Kidney allograft outcome in simultaneous pancreas-kidney transplantation.胰肾联合移植中同种异体肾移植的结果
Isr Med Assoc J. 2000 Jul;2(7):517-9.

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Spontaneous renal allograft rupture complicated by urinary leakage: case report and review of the literature.自发性肾移植破裂合并尿漏:病例报告及文献复习
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