Pontones Moreno J L, Rodrigo Aliaga M, Monserrat Monfort J J, Guillén Navarro M, Sánchez Plumed J, Jiménez Cruz J F
Servicio de Urología, Hospital Universitario La Fe, Valencia.
Actas Urol Esp. 1998 Nov-Dec;22(10):840-5; discussion 846.
Renal allograft rupture in the transplanted patient represents a usually early postoperatory complication threatening graft and patient survival. Urgent management is often required.
Renal transplanted patients which had rupture of the renal allograft have been reviewed retrospectively. Between February 1980 and June 1996 a total of 868 renal transplants were performed, and 21 (2.41%) suffered from allograft rupture. Diagnosis was based mainly on the symptoms, blood analysis to test hematocrit value, and ultrasounds.
Men age of the patients was 34 years old (21-49), 15 (71.4%) males and 6 (28.6%) females. Evolution was as follow: 4 patients underwent extracapsular nephrectomy due to non-functioning kidney; in 16 patients the graft could be preserved using different methods of renal corsetage (lyophilized human dura was applied in 8 cases, fascia lata in one, fascia lata and lyophilized human dura in 3 cases, and polyglycolic acid mesh in other 4 patients); and finally one patient was managed conservatively. There was no intra and post-operatory mortality. Four patients died lately of other causes not related to renal transplantation. Other 4 patients underwent chronic rejection and fail of the renal function. Two of these four patients have already received their second graft. A total of 13 patients have a good renal function (61.9%).
Early diagnosis of the renal allograft rupture must be the main objective in order to initiate as soon as possible therapeutic measures that firstly should be aimed to preserve the graft (medically or surgically). Nephrectomy must be reserved for renal allograft rupture secondary to venous thrombosis and other situations threatening life.
移植患者的肾移植破裂通常是一种术后早期并发症,威胁着移植肾和患者的生存。通常需要紧急处理。
对肾移植破裂的患者进行了回顾性研究。1980年2月至1996年6月期间,共进行了868例肾移植,其中21例(2.41%)发生了移植肾破裂。诊断主要基于症状、检测血细胞比容值的血液分析以及超声检查。
患者的平均年龄为34岁(21 - 49岁),男性15例(71.4%),女性6例(28.6%)。病情发展如下:4例因移植肾无功能而接受了包膜外肾切除术;16例患者通过不同的肾捆绑方法保留了移植肾(8例应用冻干人硬脑膜,1例应用阔筋膜,3例应用阔筋膜和冻干人硬脑膜,4例应用聚乙醇酸网);最后1例患者接受了保守治疗。术中及术后均无死亡病例。4例患者后期死于与肾移植无关的其他原因。另外4例发生慢性排斥反应且肾功能衰竭。这4例患者中有2例已接受了第二次移植。共有13例患者肾功能良好(61.9%)。
肾移植破裂的早期诊断必须是主要目标,以便尽快启动治疗措施,首先应旨在保留移植肾(药物或手术治疗)。肾切除术必须保留用于因静脉血栓形成和其他威胁生命的情况导致的肾移植破裂。