Marques E, Cestari I N, Cestari I A, Leirner A A
Heart Institute, University of São Paulo School of Medicine, Brazil.
Artif Organs. 1999 Jan;23(1):124-7. doi: 10.1046/j.1525-1594.1999.06266.x.
A simplified extracorporeal circulation (ECC) assemblage with autogenous oxygenation (AO) using a single centrifugal pump was tested in dogs. The transpulmonary gradient was obtained by increasing pressure in the right atrium through volume expansion and decreasing it in the left atrium by collecting the blood from the pulmonary veins in a reservoir placed below the level of the animal, generating a siphon effect. This arrangement dispenses with a right side pump. The heart was electrically fibrillated after perfusion was started and defibrillated at the end of the bypass. This ECC circuit allowed the maintenance of adequate hemodynamic and blood gas parameters during the bypass. The operating field and the mobility of the heart were equivalent to that of conventional cardiopulmonary bypass (CPB). We conclude that the use of a single centrifugal pump simplifies the autogenous oxygenation approach, making it a practical choice for the coronary artery bypass graft (CABG) procedure.
使用单个离心泵的简化体外循环（ECC）装置及自体氧合（AO）在犬身上进行了测试。通过扩容增加右心房压力，并通过将肺静脉血收集到置于动物身体水平以下的储液器中以产生虹吸效应来降低左心房压力，从而获得跨肺梯度。这种设置无需右侧泵。在灌注开始后使心脏发生电颤动，并在旁路结束时除颤。该ECC回路在旁路期间能够维持足够的血流动力学和血气参数。手术视野和心脏的活动度与传统心肺转流（CPB）相当。我们得出结论，使用单个离心泵简化了自体氧合方法，使其成为冠状动脉旁路移植术（CABG）的一个实际选择。
