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[眼球穿通伤合并眼内出血后玻璃体视网膜增殖的功能和形态学特征(免疫组织化学和电子显微镜研究)]

[Functional and morphological features of vitreoretinal proliferation after penetrating wounds of eye complicated by hemophthalmos (immunohistochemical and electron microscopy study)].

作者信息

Khoroshilova-Maslova I P, Andreeva L D, Bykov V P, Chichua G A

出版信息

Vestn Oftalmol. 1998 Nov-Dec;114(6):10-4.

PMID:9951376
Abstract

Comprehensive (optic, electron, and fluorescent microscopy) morphological analysis of vitreous fragments removed in vitrectomy after penetrating wounds of the eye complicated by hemophthalmia showed that blood and damaged cells of pigment-free ciliary epithelium and the glia play an important role in the development of proliferative processes in the ophthalmic cavity. Immunohistochemical studies revealed active expression of immunoglobulins A and G and of HLA-DR antigen on immunocompetent cells and abnormal expression of HLA-DR in pigment-free ciliary epithelium and the glia, confirming the autoimmune origin of inflammatory disorders.

摘要

对因眼球穿通伤合并眼内出血而在玻璃体切除术中摘除的玻璃体碎片进行全面(光学、电子和荧光显微镜)形态学分析显示,血液以及无色素睫状上皮和神经胶质的受损细胞在眼内腔增殖过程的发展中起重要作用。免疫组织化学研究揭示免疫球蛋白A和G以及HLA-DR抗原在免疫活性细胞上的活跃表达,以及HLA-DR在无色素睫状上皮和神经胶质中的异常表达,证实了炎症性疾病的自身免疫起源。

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