[Effects of corticosteroid and nonsteroid antiinflammatory drugs on corneal transparency after photorefraction keratectomy].

Effects of corticosteroid and nonsteroid antiinflammatory drugs on corneal transparency after photorefraction keratectomy (PFK) in myopia are studied. Corneal transparency was assessed by computer analytical system for the anterior segment of the eye, designed by the authors. Corticosteroids (0.1% dexamethasone solution) more effectively control bacterial contamination of the cornea in high myopia than nonsteroids (0.1% sodium diclofenac solution). A significant improvement of optic density of the cornea was observed 2 weeks after PFK when corticosteroids were discontinued. On the other hand, replacement of diclofenac with dexamethasone 2 weeks after PFK did not result in decrease of optic density of corneal image. Apparently, corticosteroids contribute to decrease of bacterial contamination of the cornea during the very first days after PFK. In myopia of up to -6.0 diopters, the densitometric parameters were virtually the same in the patients treated with nonsteroids and corticosteroids.