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Impairment of Hebb-Williams maze performance following prolonged alcohol consumption in rats.

作者信息

Bond N W, Di Giusto E L

出版信息

Pharmacol Biochem Behav. 1976 Jul;5(1):85-6. doi: 10.1016/0091-3057(76)90292-6.

DOI:10.1016/0091-3057(76)90292-6
PMID:996044
Abstract

Wistar rats consumed a liquid diet containing sustagen and ethanol for a period of 150 days. Control animals were pair-fed an identical diet except for isocaloric substitution of sucrose for ethanol. Forty-five days after the liquid diets were discontinued both groups were tested for performance on the Hebb-Williams maze. The experimental group made significantly more errors than the control group indicating that long-term ingestion of alcohol can lead to substantial impairment of problem-solving abilities in rats.

摘要

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